In our hyper-connected world, it should come as no surprise that recent years have shown a major uptick in the spread of transboundary pests and diseases. Integrated approaches have been effective in sustainably managing these border-jumping threats to farmers’ livelihoods and food security.
But a truly integrated approach accounts for not just the “cure,” but also how it can be sustainably incorporated into the agri-food system and social landscape. For example, how do we know if the farmers who adopt disease- and pest-resistant seed will be able to derive better incomes? And how do we ensure that incentives are aligning with community norms and values to enable better adoption of integrated disease or pest management approaches?
Experts from across the CGIAR research system and its partners weighed in on this topic in the recent webinar on Integrated Pest and Disease Management, the third in the International Year of Plant Health Webinar series. Panelists shared valuable perspectives on the science of outbreaks, the social dimensions of crop pest and disease control, zoonotic disease risk, and how national, regional and global organizations can better coordinate their responses.
“The combination of science, global partnerships and knowledge helps all of us be better prepared to avoid the losses we’ve seen. . . Today, we’re going to see what this looks like in practice,” said Rob Bertram, chief scientist for the Bureau for Resilience and Food Security at USAID, and moderator of the event.
Participants on the webinar on Integrated Pest and Disease Management. (Photo: CIMMYT)
Understanding the sources
Wheat and maize, the key crops studied at the International Maize and Wheat Improvement Center (CIMMYT) are no stranger to destructive diseases or pests, with fall armyworm, wheat blast, or maize lethal necrosis topping the list. But other staple crops and their respective economies are suffering as well — from infestations of cassava brown streak, potato cyst nematode, taro blight, desert locusts, and fusarium wilt, just to name a few.
What are the reasons for the expansion of these outbreaks? B.M. Prasanna, director of CIMMYT’s Global Maize Program explained that there are several: “Infected seed or planting material, vector movement, strong migratory capacity, contaminated field equipment, improper crop production commercialization practices, and global air and sea traffic” are all major causes.
Prevention and control of diseases and pests requires an integral strategy which mobilizes synergies of multiple institutions. (Graphic: B.M. Prasanna/CIMMYT)
Preventing outbreaks is always better than scrambling to find a cure, but as Prasanna pointed out, this requires a holistic, multi-institutional strategy including surveillance and early warning, quarantine and phytosanitary regulations, and technological solutions. Better access to monitoring and surveillance data, and sensitive, easy-to-use and affordable diagnostic equipment are essential, as is the proactive deployment of resistant crop varieties.
Building awareness about integrated disease and pest management is just as important, he told the attendees. “We must remember that IPM is not just Integrated Pest Management, but also ‘Integrating People’s Mindsets.’ That remains a major challenge. We need to think beyond our narrow disciplines and institutions and really come together to put IPM solutions into farmers’ fields,” Prasanna said.
Not all outbreaks are the same, but lessons can be shared
Regina Eddy, coordinator for the Fall Armyworm Interagency Task Force at USAID, works closely with the complex issue of scaling when it comes to disaster response and the roles of national, regional and global organizations.
“We need to develop inclusive partner stakeholder platforms, not designed ‘for them,’ but ‘with them,’” said Eddy. “We cannot tackle food security issues alone. Full stop.”
Closing the gap between social and biophysical science
Nozomi Kawarazuka, social anthropologist at the International Potato Center (CIP) explained how researchers can improve the uptake of their new seed, innovation, or agronomic practice by involving social scientists to understand the gender norms and social landscape at the beginning of the project — in the initial assessment phase.
Kawarazuka highlighted how involving women experts and extension workers in sectors that are typically male-dominated helps reduce bias and works towards changing perceptions.
“In South Asia, women farmers hesitate to engage with male government extension workers,” she said. “Women experts and extension workers reduce this barrier. Gender and social diversity in the plant health sector is an entry point to develop innovations that are acceptable to women as well as men and helps scale up adoption of innovations in the community.
Gender and social dimensions of pest and disease control: a call for collaboration (Graphic: Nozomi Kawarazuka/CIP)
The world is watching agriculture and livestock
Zoonotic diseases, or zoonoses, are caused by pathogens spread between animals and people. Understanding zoonotic disease risk is an essential and timely topic in the discussion of integrated pest management. Poor livestock management practices, lack of general knowledge on diseases and unsafe yet common food handling practices put populations at risk.
“It’s especially timely, [to have this] zoonosis discussion in our COVID-plagued planet. The whole world is going to be looking to the food and agricultural sectors to do better,” Bertram said.
Annet Mulema, a gender and social scientist at the International Livestock Research Institute (ILRI) described results of a study showing how community conversations transformed gender relations and zoonotic disease risk in rural Ethiopia, where 80% of the population depends on agriculture and has direct contact with livestock.
“There were noticeable changes in attitude and practices among men and women regarding unsafe handling of animals and consumption of animal-source foods,” Mulema explained. “Community conversations give men and women involved a voice, it allows for a variety of ideas to be expressed and discussed, leads to community ownership of conclusions and action plans, and opens communication channels among local service providers and community members.”
Proportion of women and men practicing safe handling of livestock and animal source foods, before and after community conversation intervention. (Graphic: Annet Mulema/ILRI)
Local to global, and global to local
Panelists agreed that improving capacity is the most powerful lever to advance approaches for integrated pest management and plant health, while connected and inclusive partnerships along the value chain make the whole system more resilient. The amount of scientific knowledge on ways to combat plant pests and diseases is increasing, and we have new tools to connect the global with the local and bring this knowledge to the community level.
The fourth and final CGIAR webinar on plant health is scheduled for March 31 and will focus on a the intersectional health of people, animals, plants and their environments in a “One Health” approach.
For centuries, people across Mexico and Central America have been using a traditional method, known as nixtamalization, to process their maize.
Now carried out both at household and industrial levels, this technique offers a range of nutritional and processing benefits. It could easily be adopted by farmers and consumers in other parts of the world.
What is nixtamalization?
Nixtamalization is a traditional maize preparation process in which dried kernels are cooked and steeped in an alkaline solution, usually water and food-grade lime (calcium hydroxide).
After that, the maize is drained and rinsed to remove the outer kernel cover (pericarp) and milled to produce dough that forms the base of numerous food products, including tortillas and tamales.
How does it work?
Key steps of the traditional nixtamalization process. (Graphic: Nancy Valtierra/CIMMYT)
What happens when maize kernels are nixtamalized?
The cooking (heat treatment) and steeping in the alkaline solution induce changes in the kernel structure, chemical composition, functional properties and nutritional value.
For example, the removal of the pericarp leads to a reduction in soluble fiber, while the lime cooking process leads to an increase in calcium content. The process also leads to partial starch gelatinization, partial protein denaturation — in which proteins present in the kernel become insoluble — and a partial decrease in phytic acid.
What are the benefits of processing maize in this way?
In addition to altering the smell, flavor and color of maize products, nixtamalization provides several nutritional benefits including:
Increased bioavailability of vitamin B3 niacin, which reduces the risk of pellagra disease
Increased calcium intake, due to its absorption by the kernels during the steeping process
Increased resistant starch content in food products, which serves as a source of dietary fiber
Significantly reduced presence of mycotoxins such as fumonisins and aflatoxins
Increased bioavailability of iron, which decreases the risk of anemia
These nutritional and health benefits are especially important in areas where maize is the dietary staple and the risk of aflatoxins is high, as removal of the pericarp is thought to help reduce aflatoxin contamination levels in maize kernels by up to 60% when a load is not highly contaminated.
Additionally, nixtamalization helps to control microbiological activity and thus increases the shelf life of processed maize food products, which generates income and market opportunities for agricultural communities in non-industrialized areas.
Where did the practice originate?
The word itself comes from the Aztec language Nahuatl, in which the word nextli means ashes and tamali means unformed maize dough.
Populations in Mexico and Central America have used this traditional maize processing method for centuries. Although heat treatments and soaking periods may vary between communities, the overall process remains largely unchanged.
Today nixtamalized flour is also produced industrially and it is estimated that more than 300 food products commonly consumed in Mexico alone are derived from nixtamalized maize.
Can farmers and consumers in other regions benefit from nixtamalization?
Nixtamalization can certainly be adapted and adopted by all consumers of maize, bringing nutritional benefits particularly to those living in areas with low dietary diversity.
Additionally, the partial removal of the pericarp can contribute to reduced intake of mycotoxins. Aflatoxin contamination is a problem in maize producing regions across the world, with countries as diverse as China, Guatemala and Kenya all suffering heavy maize production losses as a result. While training farmers in grain drying and storage techniques has a significant impact on reducing post-harvest losses, nixtamalization technology could also have the potential to prevent toxin contamination and significantly increase food safety when used appropriately.
If adapted, modern nixtamalization technology could also help increase the diversity of uses for maize in food products that combine other food sources like vegetables.
Nigel Poole, Professor of International Development at SOAS, University of London, writes on The Conversation about the role of cereals in fighting malnutrition. Poole was a Visiting Fellow at the International Maize and Wheat Improvement Center (CIMMYT) in Mexico for a year.
Agricultural knowledge management framework for innovation (AKM4I) in agri-food systems. (Graphic: CIMMYT)
The key to transforming food production systems globally lies in knowledge management processes, according to a team of researchers from the International Maize and Wheat Improvement Center (CIMMYT).
The challenge is to combine traditional knowledge with state-of-the-art scientific research: to meet regional needs for improvement in farming systems with knowledge networks fostering innovative practices and technologies that increase yields and profits sustainably.
A group of CIMMYT researchers led by Andrea Gardeazábal, Information and Communications Technology for Agriculture Monitoring and Evaluation Manager, recently published a proposal for a new knowledge management framework for agri-food innovation systems: Agricultural Knowledge Management for Innovation (AKM4I).
“We are proposing a knowledge management framework for agricultural innovation that addresses the need for more inclusive and environmentally sustainable food production systems that are able to provide farmers and consumers with affordable and healthy diets within planetary boundaries,” Gardeazábal said.
The AKM4I framework was designed to help agricultural development practitioners understand how farming skills and abilities are developed, tested and disseminated to improve farming systems in real-life conditions.
Following systems theory principles, the model empirically describes how information is created, acquired, stored, analyzed, integrated and shared to advance farming knowledge and produce innovative outcomes that effectively contribute to: collaboratively building local capacities for developing joint problem-solving abilities and integrated-knowledge solutions; empowering farmers with site-specific knowledge; co-creating technology and conducting participatory community-based research; and bridging innovation barriers to drive institutional change.
Knowledge access for systems transformation
Schematic illustration of CIMMYT’s knowledge and technology development networks, or hubs, for sustainable maize and wheat production systems. (Graphic: CIMMYT)
The framework builds on CIMMYT’s learnings from MasAgro, a bilateral project with Mexico that relies on participatory research and knowledge and technology development networks for sustainable maize and wheat production systems.
This CIMMYT project was recently acknowledged with the 2020 Innovative Applications in Analytics Award for developing groundbreaking monitoring, evaluation, accountability and learning (MEAL) systems and tools for publicly funded researchers and field technicians who advise more than 150,000 farmers in Mexico.
“Through the outlined principles and processes, the AKM4I framework can assist in closing the cycle of continually re-creating knowledge, evaluating and iterating upon innovations, building coalitions to democratize knowledge access and utilization, and using MEAL to facilitate course-correction of all stages of knowledge management,” concludes the study.
Seed viability test at the CIMMYT genebank. (Photo: Alfonso Cortés/CIMMYT)
The conservation of plant genetic diversity through germplasm conservation is a key component of global climate-change adaptation efforts. Germplasm banks like the maize and wheat collections at the International Maize and Wheat Improvement Center (CIMMYT) may hold the genetic resources needed for the climate-adaptive crops of today and tomorrow.
But how do we ensure that these important backups are themselves healthy and not potential vectors of pest and disease transmission?
“Germplasm refers to the source plants of either specific cultivars or of unique genes or traits that can be used by breeders for improved cultivars,” program moderator and head of the Health and Quarantine Unit at the International Potato Center (CIP) Jan Kreuze explained to the event’s 622 participants. “If the source plant is not healthy, whatever you multiply or use it for will be unhealthy.”
According to keynote speaker Saafa Kumari, head of the Germplasm Health Unit at the International Center for Agricultural Research in the Dry Areas (ICARDA), we know of 1.3 thousand pests and pathogens that infect crops, causing approximately $530 billion in damages annually. The most damaging among these tend to be those that are introduced into new environments.
Closing the gap, strengthening the safety net
The CGIAR has an enormous leadership role to play in this area. According to Kumari, approximately 85% of international germplasm distribution is from CGIAR programs. Indeed, in the context of important gaps in the international regulation and standards for germplasm health specifically, the practices and standards of CGIAR’s Germplasm Health Units represent an important starting point.
“Germplasm health approaches are not necessarily the same as seed and plant health approaches generally,” said Ravi Khaterpal, executive secretary for the Asia-Pacific Association of Agricultural Research Institutions (APAARI). “Best practices are needed, such as CGIAR’s GreenPass.”
In addition to stronger and more coherent international coordination and regulation, more research is needed to help source countries test genetic material before it is distributed, according to Francois Petter, assistant director for the European and Mediterranean Plant Protection Organization (EPPO). Head of the CGIAR Genebank Platform Charlotte Lusty also pointed out the needed for better monitoring of accessions in storage. “We need efficient, speedy processes to ensure collections remain healthy,” she said.
Of course, any regulatory and technological strategy must remain sensitive to existing and varied social and gender relations. We must account for cultural processes linked to germplasm movement, said Vivian Polar, Gender and Innovation Senior Specialist with the CGIAR Research Program on Roots, Tubers and Bananas (RTB). Germplasm moves through people, she said, adding that on the ground “women and men move material via different mechanisms.”
“The cultural practices associated with seed have to be understood in depth in order to inform policies and address gender- and culture-related barriers” to strengthening germplasm health, Polar said.
The event was co-organized by researchers at CIP and the International Institute of Tropical Agriculture (IITA).
The overall webinar series is hosted by CIMMYT, CIP, the International Food Policy Research Institute (IFPRI), IITA, and the International Rice Research Institute (IRRI). It is sponsored by the CGIAR Research Program on Agriculture for Nutrition (A4NH), the CGIAR Gender Platform and the CGIAR Research Program on Roots, Tubers and Bananas (RTB).
The third of the four webinars on plant health, which will be hosted by CIMMYT, is scheduled for March 10 and will focus on integrated pest and disease management.
Global thought leader, philanthropist and one of the International Maize and Wheat Improvement Center (CIMMYT) and CGIAR’s most vocal and generous supporters, Bill Gates, wrote a book about climate change and is now taking it around the world on a virtual book tour to share a message of urgency and hope.
With How to Avoid a Climate Disaster, Gates sets out a holistic and well-researched plan for how the world can get to zero greenhouse gas emissions in time to avoid a climate catastrophe. Part of this plan is to green everything from how we make things, move around, keep cool and stay warm, while also considering how we grow things and what can be done to innovate agriculture to lower its environmental impact.
Interviewed by actor and producer Rashida Jones, Gates explained his passion for action against climate change: “Avoiding a climate disaster will be one of the greatest challenges us humans have taken on. Greater than landing on the moon, greater than eradicating smallpox, even greater than putting a computer on every desk.”
“The world needs many breakthroughs. We need to get from 51 billion tons [of greenhouse gases] to zero while still meeting the planet’s basic needs. That means we need to transform the way we do almost everything.”
Bill Gates (left) talks to Rashida Jones during one of the events to present his new book.
Innovations in agriculture
When a book tour event attendee asked about the role of agriculture research in improving farmers’ livelihoods, Gates linked today’s challenge to that of the Green Revolution more than half a century ago. “There’s nothing more impactful to reduce the impacts of climate change than working on help for farmers. What we can do this time is even bigger than that. […] The most unfunded thing in this whole area is the seed research that has so much potential,” he said.
One such innovation and one of Gates’ favorite examples of CGIAR’s work is featured in Chapter 9 of his climate book – “Adapting to a warmer world” – and has been the source of generous funding from the Bill & Melinda Gates Foundation: drought-tolerant maize. “[…] as weather patterns have become more erratic, farmers are at greater risk of having smaller maize harvests, and sometimes no harvest at all. So, experts at CGIAR developed dozens of new maize varieties that could withstand drought conditions, each adapted to grow in specific regions of Africa. At first, many smallholder farmers were afraid to try new crop varieties. Understandably so. If you’re eking out a living, you won’t be eager to take a risk on seeds you’ve never planted before, because if they die, you have nothing to fall back on. But as experts worked with local farmers and seed dealers to explain the benefits of these new varieties, more and more people adopted them,” writes Gates.
We at CIMMYT are very proud and humbled by this mention as in collaboration with countless partners, CIMMYT and the International Institute of Tropical Agriculture (IITA) developed and promoted these varieties across 13 countries in sub-Saharan Africa and contributed to lifting millions of people above the poverty line across the continent.
For example, in Zimbabwe, farmers who used drought-tolerant maize varieties in dry years were able to harvest up to 600 kilograms more maize per hectare — enough for nine months for an average family of six — than farmers who sowed conventional varieties.
The world as we know it is over and, finally, humanity’s fight against climate change is becoming more and more mainstream. CIMMYT and its scientists, staff, partners and farmers across the globe are working hard to contribute to a transformation that responds to the climate challenge. We have a unique opportunity to make a difference. It is in this context that CGIAR has launched an ambitious new 10-year strategy that echoes Gates’s hopes for a better environment and food security for the generations to come. Let’s make sure that it ticks the boxes of smallholder farmers’ checklists.
A shop attendant displays drought-tolerant maize seed at the Dryland Seed Company shop in Machakos, Kenya. (Photo: Florence Sipalla/CIMMYT)
For several decades, the International Maize and Wheat Improvement Center (CIMMYT) has worked with partners and farmers to improve maize and wheat varieties. Packed with “upgrades” such as tolerance to environmental stresses, tolerance to diseases and pests, boosted nutrient content, higher yield potential and storage capabilities, and improved efficiency in using water and fertilizers, these seeds are rolled out by CIMMYT and its partners to create new opportunities for easier and better lives for farmers.
Together with national research partners, farmers, local governments and seed companies, CIMMYT’s work in seed systems has reaped results. Its experts are eager to put this experience into further action as CGIAR embarks on the next ten years of its journey to transform food, land, and water systems in a climate crisis. And rightly so: investments in CGIAR research — mainly through their contributions to enhancing yields of staple food crops — have returned ten-fold benefits and payoffs for poor people in terms of greater food abundance, lower prices of food, reduced food insecurity and poverty and reduced geographical footprint of agriculture. A large part of this impact is the result of CIMMYT’s day to day efforts to create a better world.
A Bangladeshi woman cuts up feed for her family’s livestock. They did not previously have animals, but were able to buy them after her husband, Gopal Mohanta, attended a farmer training from CIMMYT and its partners, which gave him access to better seed, technologies, and practices. Mohanta planted a wider range of crops, and in 2005 he planted maize for the first time, using improved seed based on CIMMYT materials. (Photo: S. Mojumder/Drik/CIMMYT)
Replacing old varieties, not as easy as it sounds
Slow variety turnover — that of more than ten years — makes farmers vulnerable to risks such as climate change and emerging biotic threats. On the other hand, planting improved varieties that match farmers’ needs and the geography they work in, can increase productivity gains and improve the nutritional status of smallholders and their families. This, in turn, contributes to increased household incomes. Indirectly, the benefits can reach the surrounding community by providing increased employment opportunities, wage increases and affordable access to food.
Despite its tremendous benefits, varietal turnover is no small feat.
When it comes to seeds, detailed multi-disciplinary research is behind every new variety and its deployment to farmers. Just as the production of a new snack, beverage or a car requires an in-depth study of what the customer wants, seed systems also must be demand-driven.
Socioeconomists have to work hand-in-hand with breeders and seed system specialists to understand the drivers and bottlenecks for improved varietal adoption, market needs, and gender and social inclusion in seed delivery. Bottlenecks include the lack of access by farmers — especially for resource-poor, socially-excluded ones — to reliable information about the advantages of new varieties. Even if farmers are aware of new varieties, seeds might not be available for sale where they live or they might be too expensive.
Possibly the most complex reason for slow variety turnover is risk vulnerability: some farmers simply can’t afford to take the risk of investing in something that might be good but could also disappoint. At the same time, seed companies also perceive a certain risk: they might not be interested in taking on an improved variety that trumps the seeds from older but more popular varieties they have on stock. For them, building and marketing a new brand of seeds requires significant investments.
Agricultural seed on sale by a vendor near Islamabad, Pakistan. For improved crop varieties to reach farmers, they usually must first reach local vendors like these, who form an essential link in the chain between researchers, seed producers and farmers. (Photo: M. DeFreese/CIMMYT)
New approaches are yielding results
Despite the complexity of the challenge, CIMMYT has been making progress, especially in Africa where slow variety turnover is creating roadblocks for increased food security and poverty alleviation.
Recent analysis of the weighted average age of CIMMYT-related improved maize varieties in 8 countries across eastern and southern Africa reveals that the overall weighted average age has decreased from 14.6 years in 2013 to 10.2 years in 2020. The remarkable progress in accelerating the rate of variety turnover and deploying the improved genetics — with climate resilience, nutritional-enhancement and grain yield — are benefiting more than eight million smallholders in Africa.
In Ethiopia, CIMMYT, EIAR and ICARDA’s work led to the adoption of improved rust-resistant varieties, corresponding productivity gains and economic benefits that, besides the urgent need to fight against the damaging rust epidemic, depended on a combination of enabling factors: pre-release seed multiplication, pro-active policies and rust awareness campaigns. The estimated income gain that farmers enjoyed due to adopting post-2010 varieties in 2016/2017 reached $48 million. For the country itself, the adoption of these varieties could save $65 million that otherwise would be spent on wheat imports.
Bill Gates echoes this in Chapter 9 of his new climate book, How to Avoid a Climate Disaster, as he describes CIMMYT and IITA’s drought-tolerant maize work: “[…] experts at CGIAR developed dozens of new maize varieties that could withstand drought conditions, each adapted to grow in specific regions of Africa. At first, many smallholder farmers were afraid to try new crop varieties. Understandably so. If you’re eking out a living, you won’t be eager to take a risk on seeds you’ve never planted before, because if they die, you have nothing to fall back on. But as experts worked with local farmers and seed dealers to explain the benefits of these new varieties, more and more people adopted them.”
Bidasem director general María Ester Rivas (center) stands for a photo with her seed processing team. Bidasem is a small seed company based in the city of Celaya in the central Mexican plains region known as the Bajío. Despite their small size, Bidasem and similar companies play an important role in reaching small farmers with improved seed that offers them better livelihoods. (Photo: X. Fonseca/CIMMYT)
Holistic action needed if we are to reach farmers with genetic innovations
Now more than ever, with increased frequency and intensification of erratic weather events on top of the complications of the COVID-19 pandemic, successful seed systems require the right investments, partnerships, efforts across disciplines, and enabling policies.
Varietal release and dissemination systems rely greatly on appropriate government policies and adoption of progressive seed laws and regulations. CGIAR’s commitment to farmers and the success of national seed systems is described in the recently launched 10-year strategy: “CGIAR will support effective seed systems by helping national governments and private sector companies and regulators build their capacities to play their roles successfully. New initiatives will be jointly designed along the seed distribution chain, including for regional seed registration, import and export procedures, efficient in-country trialing, registration and release of new varieties, and seed quality promotion through fit-for-purpose certification.”
In line with CGIAR’s ambitious goals, to provide farmers with a better service, small- and medium-size seed companies need to also be strengthened to become more market-oriented and dynamic. According to SPIA, helping local private seed dealers learn about new technology increases farm-level adoption by over 50% compared to the more commonly used approach, where public sector agricultural extension agents provide information about new seed to selected contact farmers.
CIMMYT socioeconomics and market experts are putting this in practice through working with agrodealers to develop retail strategies, such as targeted marketing materials, provision of in-store seed decision support and price incentives, to help both female and male farmers get the inputs that work best.
Within the new CGIAR, CIMMYT scientists will continue to work with partners to strongly improve the performance of wheat and maize in smallholder farmers’ fields. Concerted efforts from all actors conforming the entire seed system are essential to achieve our vision: to transform food systems for affordable, sufficient and healthy diets produced within planetary boundaries. Wheat and maize seed systems will form the basis to fulfill that vision and provide a tried and tested roadmap for other crops, including legumes, vegetables and fruits. Together, we can keep a finger on the pulse of farmers’ needs and build healthy diets for a better tomorrow from the ground up.
Haploids — which are produced naturally in maize — were first identified in the crop about a century ago. Today they are used widely in different breeding programs, particularly in the development of doubled haploids, which are highly uniform, genetically pure and stable. Doubled-haploid technology has simplified logistics to make the maize breeding process more efficient and intuitive, facilitated studies at the molecular and genomic level, and increased genetic gains in different breeding programs.
In a recent review article, scientists from the International Maize and Wheat Improvement Center (CIMMYT) examine strategies for haploid induction and identification, chromosome doubling and production of doubled haploid seed through self-fertilization. They also discuss the potential applications and key challenges linked with doubled haploid technology in maize, and suggest future research directionsfor people involved in fast-track maize breeding, the seed industry, and academia.
Extensive studies of haploids and doubled haploids have increased our understanding of the genetic basis and mechanisms involved in haploid induction, the factors that affect haploid induction, different markers to identify putative haploids, and different chemicals agents that can be used for chromosome doubling.
The technology is useful because the resulting plants are free from different social issues and legal regulations associated with transgenic crops. It maximizes genetic gains in breeding programs, is one of the fastest tools available for developing large numbers of inbred lines quickly and reduces the cost of breeding programs.
“Deployment of doubled haploid technology is much needed for commercial hybrid maize breeding programs to make them more efficient and economical,” says article co-author Abdurahman Beshir, a maize seed systems specialist based in Nepal. “The technology is also useful to have accelerated varietal turnover and a higher maize seed replacement rate in different market segments.”
Many multinational seed companies have adopted doubled haploid technology for the wide-scale production of inbred lines. The development of novel techniques for haploid induction and the subsequent production of doubled haploid plants holds significant potential for the management of genetic resources, germplasm enhancement and the development of novel plant populations.Researchers at CIMMYT have also made significant efforts to help national breeding programs adopt this technology, especially in South Asia, where the organisation has shared haploid inducers with numerous partners in Pakistan.
But, while this technology can accelerate maize breeding, it still faces challenges at each step of doubled haploid line development and the authors argue there is a need to extensively explore the genetic potential of this technology to continue increasing the genetic gains associated with different breeding programs.
Cover image: A mixture ofdoubledhaploidmaizekernelsseen in close-up at CIMMYT’s Agua Fria experimental station in Mexico. (Photo: Alfonso Cortés/CIMMYT)
Read more new publications from CIMMYT researchers:
A leader of wheat breeding and later director of CIMMYT’s Global Wheat Program, Sanjaya Rajaram passed away at the age of 78.
Recognized with the World Food Prize in 2014, he personally oversaw the development of more than 480 high-yielding, disease-resistant varieties sown on 58 million hectares in 51 countries, increasing global wheat production by more than 200 million tons during his lifetime in diverse regions across the globe.
Wheat infected with the blast fungus in Meherpur, Bangladesh, in 2019. (Photo: PLOS Biology)
As scientists study and learn more about the complicated genetic makeup of the wheat genome, one chromosomal segment has stood out, particularly in efforts to breed high-yielding wheat varieties resistant to devastating and quickly spreading wheat diseases.
Known as the 2NvS translocation, this segment on the wheat genome has been associated with grain yield, tolerance to wheat stems bending over or lodging, and multiple-disease resistance.
Now, thanks to a new multi-institution study led by wheat scientist Liangliang Gao of Kansas State University, we have a clearer picture of the yield advantage and disease resistance conferred by this chromosomal segment for wheat farmers — and more opportunities to capitalize on these benefits for future breeding efforts.
The Aegilops ventricosa 2NvS segment in bread wheat: cytology, genomics and breeding, published in Theoretical and Applied Genetics, summarizes the collaborative effort by scientists from several scientific institutions — including International Maize and Wheat Improvement Center (CIMMYT) head of global wheat improvement Ravi Singh and wheat scientist Philomin Juliana — to conduct the first complete cytological characterization of the 2NvS translocation.
A rich background
The 2NvS translocation segment has been very valuable in disease-resistance wheat breeding since the early 1990s. Originally introduced into wheat cultivar VPM1 by the French cytogeneticist Gerard Doussinault in 1983 by crossing with a wild wheat relative called Aegilops ventricosa, the segment has been conferring resistance to diseases like eye spot (Pch1 gene), leaf rust (Lr37 gene), stem rust (Sr38 gene), stripe rust (Yr17 gene), cereal cyst (Cre5 gene), root knot (Rkn3 gene) and wheat blast.
The high-yielding blast-resistant CIMMYT-derived varieties BARI Gom 33 and WMRI#3 (equivalent to Borlaug100),released in Bangladesh to combat a devastating outbreak of wheat blast in the region, carry the 2NvS translocation segment for blast resistance.
Earlier research by Juliana and others found that the proportion of lines with the 2NvS translocation had increased by 113.8% over seven years in CIMMYT’s international bread wheat screening nurseries: from 44% in 2012 to 94.1% in 2019. It had also increased by 524.3% in the semi-arid wheat screening nurseries: from 15% in 2012 to 93.7% in 2019. This study validates these findings, further demonstrating an increasing frequency of the 2NvS translocation in spring and winter wheat breeding programs over the past two decades.
New discoveries
The authors of this study completed a novel assembly and functional annotation of the genes in the 2NvS translocation using the winter bread wheat cultivar Jagger. They validated it using the spring wheat cultivar CDC Stanley and estimated the actual size of the segment to be approximately 33 mega base pairs.
Their findings substantiate that the 2NvS region is rich in disease resistance genes, with more than 10% of the 535 high-confidence genes annotated in this region belonging to the nucleotide-binding leucine-rich repeat (NLR) gene families known to be associated with disease resistance. This was a higher number of NLRs compared to the wheat segment of the Chinese Spring reference genome that was replaced by this segment, adding further evidence to its multiple-disease resistant nature.
In addition to being an invaluable region for disease resistance, the study makes a strong case that the 2NvS region also confers a yield advantage. The authors performed yield association analyses using yield data on lines from the Kansas State University wheat breeding program, the USDA Regional Performance Nursery —comprising lines from central US winter wheat breeding programs — and the CIMMYT spring bread wheat breeding program, and found a strong association between the presence of the segment and higher yield.
Global benefits
The yield and disease resistance associations of the 2NvS genetic segment have been helping farmers for years, as seen in the high proportion of the segment present in the improved wheat germplasm distributed globally through CIMMYT’s nurseries.
“The high frequency of the valuable 2NvS translocation in CIMMYT’s internationally distributed germplasm demonstrates well how CIMMYT has served as a key disseminator of lines with this translocation globally that would have likely contributed to a large impact on global wheat production,” said study co-author Juliana.
Through CIMMYT’s distribution efforts, it is likely that national breeding programs have also effectively used this translocation, in addition to releasing many 2NvS-carrying varieties selected directly from CIMMYT distributed nurseries.
With this study, we now know more about why the segment is so ubiquitous and have more tools at our disposal to use it more deliberately to raise yield and combat disease for wheat farmers into the future.
The new interactive map allows visitors to visually explore the milestones that allowed a global network of researchers to fight threats to wheat production.
In 2005, preeminent wheat breeder and Nobel Laureate Norman E. Borlaug sounded the alarm to bring the world’s attention to the outbreak of a new variant of stem rust, Ug99, that threatened to wipe out 80% of the world’s wheat.
The result was the Borlaug Global Rust Initiative (BGRI), a global community that pioneered innovative ways for scientists and smallholder farmers around the globe to collaborate on meeting challenges brought about by wheat disease and climate change.
As a founding member of BGRI, the International Maize and Wheat Improvement Center (CIMMYT) and, later, the CGIAR Research Program on Wheat, played a crucial role in the core work of the initiative. They led breeding and large-scale international testing to develop disease resistant wheat varieties, coordinated closely with longstanding national partners to facilitate the release and spread of the varieties to farmers, and contributed to critical disease monitoring and tracking initiatives.
The BGRI has documented these efforts and related resources in a newly released interactive story map: Inside the global network safeguarding the world’s wheat from disease and climate change. The map highlights the BGRI’s efforts from 2005 to 2020 to introduce climate-resilient, disease-resistant wheat to resource-constrained wheat growers around the world, especially in sub-Saharan Africa and South Asia.
When a disease threatens to destroy the world’s most important food crop, who do you call?
The map highlights work undertaken by scientists on the front lines of the Durable Rust Resistance in Wheat (DRRW) and Delivering Genetic Gain in Wheat (DGGW) projects from 2005 to 2020. These achievements formed the foundation for the work that continues today under the auspices of the CIMMYT-led Accelerating Genetic Gains In Maize and Wheat for Improved Livelihoods (AGG) project.
BGRI scientists from more than 22 national and international agricultural research centers infused resilience into wheat and largely staved off large-scale rust epidemics, working with farmers in East Africa, South Asia and other important bread baskets of the world. The BGRI community improved breeding pipelines, created the world’s most sophisticated pathogen surveillance network, increased capacity in germplasm testing nurseries while conserving and sharing genetic resources, and training new generations of young scientists.
Through videos, photos, interviews, journal articles, blogs, news stories and other resources, the map allows visitors to explore the multifaceted work from hunger fighters in Australia, Canada, China, Ethiopia, India, Kenya, Mexico, Nepal, Russia, the United Kingdom, the United States and other countries.
Written and produced by BGRI cinematographer Chris Knight and associate director for communications Linda McCandless, the map is linked to multimedia and resources from contributors around the world.
The DRRW and DGGW projects received funding from the Bill & Melinda Gates Foundation, the UK Foreign, Commonwealth and Development Office, national research institutes, and Cornell University.
Accelerating Genetic Gains in Maize and Wheat for Improved Livelihoods (AGG) brings together partners in the global science community and in national agricultural research and extension systems to accelerate the development of higher-yielding varieties of maize and wheat — two of the world’s most important staple crops. Funded by the Bill & Melinda Gates Foundation, the UK Foreign, Commonwealth & Development Office (FCDO), the U.S. Agency for International Development (USAID) and the Foundation for Food and Agriculture Research (FFAR), AGG fuses innovative methods that improve breeding efficiency and precision to produce and deliver high-yielding varieties that are climate-resilient, pest- and disease-resistant, highly nutritious, and targeted to farmers’ specific needs.
Research reported in this story was supported by the Foundation for Food and Agriculture Research under award number Grant ID COTF0000000001. The content of this publication is solely the responsibility of the authors and does not necessarily represent the official views of the Foundation for Food and Agriculture Research.
A CIMMYT technician cuts a leaf sample for DNA extraction. (Photo: CIMMYT)
Wheat breeders from across the globe took a big step towards modernizing their molecular breeding skills at a recent workshop sponsored by the Wheat Initiative, with the CGIAR Excellence in Breeding Platform (EiB) and the International Maize and Wheat Improvement Center (CIMMYT).
The workshop focused on three open-source tools used in molecular breeding: GOBii-GDM for genomic data management, Flapjack for data visualization and breeding analysis, and Galaxy for Genomic Selection. These tools help breeders make selections more quickly and precisely, and ultimately lead to more cost effective and efficient improvement of varieties.
The Wheat Initiative — a global scientific collaboration whose goals are to create improved wheat varieties and disseminate better agronomic practices worldwide — and its Breeding Methods and Strategies expert working group had planned to host these trainings during the 2020 Borlaug Global Rust Initiative Technical Workshop in the United Kingdom. After it became obvious that in-person trainings were not possible, the course organizers — including CIMMYT molecular wheat breeder Susanne Dreisigacker and EiB Adoption Lead and former GOBii project director Elizabeth Jones — decided to come together to host online workshops.
Many of the tools will be incorporated into EiB’s Enterprise Breeding System (EBS), a new integrated data management system being developed for CGIAR breeders. Jones plans to also design training modules for these molecular breeding tools that will be accessible to anyone through the EiB Toolbox.
The first session of the workshop “Transforming Wheat Breeding Through Integrated Data Management with GOBii and Analysis in Flapjack” benefited breeders from Australia, Canada, Ethiopia, France, India, Ireland, Italy, Morocco, Pakistan, Switzerland, Tunisia, the United Kingdom and the United States.
Susanne Dreisigacker presents during one of the sessions of the workshop.
Powering data analysis around the world
The workshop series, “Transforming Wheat Breeding Through Integrated Data Management with GOBii and Analysis in Flapjack,” aimed to benefit breeders from wheat producing countries all over the world, with sessions over two different time zones spread out over three days to reduce “Zoom fatigue.” Participants joined the first session from Australia, Canada, Ethiopia, France, India, Ireland, Italy, Morocco, Pakistan, Switzerland, Tunisia, the United Kingdom and the United States.
“It was wonderful to see the diversity of participants that we were able to train through an online workshop, many of whom otherwise might not have been able to travel to the UK for the original meeting,” said Jones. “Participants were very engaged, making the workshop so rewarding.”
The workshop was guided by Teresa Saavedra, Wheat Initiative coordinator. Apart from Dreisigacker and Jones, other trainers explained specific tools and approaches. Iain Milne from the James Hutton Institute in Scotland gave more details about the Flapjack genotyping visualization tool, which includes analysis for pedigree verification, marker assisted backcrossing and forward breeding. Andrew Kowalczyk, developer at Diversity Arrays Technology, spoke about the genotyping data QC tool DArTView.
A CIMMYT technician performs one of the steps to extract DNA samples from plants. (Photo: CIMMYT)
Clay Sneller, wheat breeder at Ohio State University, contributed training materials for important molecular breeding tools. Carlos Ignacio, previously based at the International Rice Research Center (IRRI) and now working on a PhD in Genomic Selection at Ohio State University, contributed his experience as a GOBii team member and a major contributor towards the design of Flapjack tools. Star Gao, application specialist with GOBii and now a requirements analyst for the Enterprise Breeding System, also facilitated the sessions.
Gilles Charmet, research director at the France’s National Research Institute for Agriculture, Food and Environment (INRAE), introduced the sessions in the Americas/Europe time zone with welcome remarks and overview of the goals of the Wheat Initiative. Alison Bentley, director of the CIMMYT Global Wheat Program, briefed on the achievements and goals of the CIMMYT Wheat program and the Accelerating Genetic Gains in Maize and Wheat for Improved Livelihoods (AGG) project.
“This training will contribute towards us reaching our AGG goals of accelerating gains in wheat, by sharing technical knowledge, and allowing our beneficiary partners to have state-of-the-art know-how in the use of genetic and genomic data,” Bentley said.
Participant Stéphane Boury from Caussade Semences, France commented, “This was a very effective way to learn about new tools in wheat breeding.”
The sessions continue in Australasia next week, and will be introduced by Peter Langridge, chair of the Scientific Board for the Wheat Initiative, and EiB director Michael Quinn. Sanjay Kumar Singh, incoming chair of the Breeding expert working group for the Wheat Initiative, will close the event.
Denise E. Costich, the recently retired head of the Maize Collection at the Germplasm Bank of the International Maize and Wheat Improvement Center (CIMMYT), sometimes likes to include a Woody Allen quote in her presentations.
“I have no idea what I’m doing,” declares the text over a photo of a befuddled-looking Allen. “But incompetence never stopped me from plunging in with enthusiasm.”
This is perhaps Costich’s tongue-in-cheek way of acknowledging the unusual trajectory that led her to the Germplasm Bank and her zeal for new and interesting challenges. But it is in no way an accurate reflection of the skill, knowledge and humane managerial style she brought to the job.
“CIMMYT requires individuals with a broad set of experiences,” says Tom Payne, head of the Wheat Collection at CIMMYT’s Germplasm Bank. Though she was not trained as a crop scientist, and despite having never worked in a genebank before, Costich’s rich set of professional and life experiences made her an ideal person for the job.
From Ithaca and back again
Born and raised in Westbury, NY, Costich spent much of her childhood on a tree nursery. Her grandfather was the manager, her father became the sales director and eventually her sister also went into the horticulture business. While her experiences on the nursery contributed to an early interest in plants and ecology, the business aspect of the nursery eluded her. “I just can’t sell things. I’m terrible,” Costich says. “But I really do like to study them.”
This studiousness took her to Cornell University in Ithaca, NY, where she initially declared as a wildlife biology major. Her notion of what it meant to “study things” was influenced by her early heroes, primatologists and field biologists Dian Fossey and Jane Goodall. It involved travel. Fieldwork in faraway places. So, when the opportunity arose at the end of her sophomore year to travel to Kenya with Friends World College, Costich didn’t hesitate.
Costich eventually spent four years in Kenya, studying baboons. When she finally returned to Ithaca, she knew two things. Fieldwork was absolutely her thing, and she wanted to pursue a doctorate.
A chance conversation with her housemates in her last semester led to a post-graduation fieldwork stint in the Brazilian Amazon under the supervision of the legendary tropical and conservation biologist, Thomas Lovejoy. But instead of a dissertation topic, she stumbled across a parasite, a case of leishmaniasis and the realization that the rainforest was not the work environment for her.
Unexpected influences and outcomes continued to mark Costich’s career throughout her graduate studies at the University of Iowa. She found her plant not in the field, but while reading a dusty review paper as an exchange student at the University of Wisconsin. Her study of Ecballium elaterium (a wild species in the Cucurbitaceae, or squash, family) did not take her back to the tropics — where most of her peers were working and where she expected to be headed as a grad student — but rather to Spain where, incidentally, she first learned Spanish.
Several years after defending, Costich landed a tenure-track position in the Biology Department at The College of New Jersey. She continued to publish on Ecballium elaterium. Her career appeared to be settling into a predictable, recognizable academic trajectory — one with no obvious intersection with CIMMYT.
Then Costich saw an ad in the Ecological Society of America bulletin for a managing editor position for all of the Society’s journals. Her husband, a fellow biology Ph.D., had been working as an academic journal editor for several years. When Costich saw the ad she immediately drove over to her husband’s office. “I slapped the thing on his desk and said, ‘Here’s your job!’” she recalls.
Costich was right. Soon after, she was on her way back to Ithaca — where the Society’s offices were located — with a family that now included three children. While it was the right move for her family, it came at the cost of her budding academic career. In Ithaca, she soon found herself stuck in the role of itinerant postdoc.
Denise Costich in Spain in 1986, doing fieldwork on Ecballium elaterium with her daughter Mara.
An amazing turn of events
Costich admits that, especially the beginning, the return to Ithaca was tough, even depressing. Her recollections of these years can sound a bit like a game of musical chairs played with research laboratories. As one post-doc or research project wound down, she’d find herself scanning the campus for her next perch. She became very adept at it. “In ten years, I never missed a paycheck,” Costich says.
The turn of the millennium found Costich scanning the horizon yet again. As the days wound down at her latest post, a maize geneticist moved into the lab next door. What started as hallway jokes about Costich jumping ship and joining the maize lab soon turned into an interview, then a job offer.
The job introduced her to nearly everyone at Cornell working in maize genetics. Costich soon found herself managing the Buckler Lab’s work on maize population genetics. Meanwhile, she dabbled in side projects on Tripsacum, a perennial grass genus that is closely related to maize, and managed a major project on switchgrass. At the end of her postdoc, Buckler set to work trying to create a permanent position for her. Once again, Costich’s trajectory was beginning to take a stable, predictable form.
Then CIMMYT scientist Sarah Hearne showed up. “I’d heard through the grapevine — or maybe through the corn field — that the position of manager of the Maize Collection of CIMMYT’s Germplasm Bank was open… and that they were having a hard time trying to find a person for the position,” Costich recalls. She had met Hearne previously and personally knew and had worked with Suketoshi Taba, the pioneering longtime director of the germplasm bank. Naturally the topic emerged as she and Hearne caught up in Ithaca.
Hearne admitted that the search hadn’t yet been successful. “But I know the perfect person for the job,” she added.
“Yeah, who’s that?” Costich asked, not getting the setup.
Denise Costich, the maize collection manager at CIMMYT’s Maize and Wheat Germplasm Bank, shows one of the genebank’s more than 28,000 accessions of maize. (Photo: Luis Salazar/Crop Trust)
A stranger in a strangely familiar land
Costich was not a little surprised by the suggestion. She had never worked at a germplasm bank before. She was finally finding some stability at Cornell.
At the same time, her early dreams of exploring new places through her work, especially the tropics, beckoned. Her youngest son was nearly college-aged. Against the advice of some who had watched her work so hard to establish herself at Cornell, she took the plunge.
By the time she reached the CIMMYT campus in Texcoco, Costich had crisscrossed a good part of the globe, picking up Spanish here, management skills there, a deep knowledge of maize and its biological and cultural evolution yonder. During this life journey, she developed a deep humanism that is all her own.
It all seemed like happenstance, perhaps, until she reached Mexico and — suddenly, counterintuitively — found herself in the field she was perfectly adapted for. “It turned out that being a germplasm bank manager was the perfect job for me, and I didn’t even know it!” Costich says. “I ended up using everything I learned in my entire career.”
That isn’t to say that it was easy, especially at first. Taba, her predecessor, had occupied the post for decades, was a trained crop scientist, and had grown the bank from a regionally-focused collection with 12,000 accessions to the preeminent maize germplasm bank globally with 28,000 accessions, a state-of-the-art storage facility, and a slew of pioneering practices.
Not only had Taba left enormous shoes to fill, during his tenure — as is common in the expansionary phase of many projects — it had been difficult for the bank to keep a full accounting and understanding of all the new material that had been added. According to germplasm bank coordinator Cristian Zavala, by the time Costich joined CIMMYT “we knew very little about the material in our vaults.”
“Taba was primarily a breeder,” Costich says. “I actually think this oscillation between a focus on breeding and a focus on conservation and curation is good for the bank.”
Visiting a newly-built community seed reserve in Chanchimil, Todos Santos Cuchumatanes, Huehuetenango, Guatemala, in 2016. From left to right: Mario Fuentes (collaborator), a member of the community seed reserve staff, Denise Costich, Carolina Camacho (CIMMYT), Miriam Yaneth Ramos (Buena Milpa) and Esvin López (local collaborator).
Visiting one of the oldest community seed reserves in the region, Quilinco, Huehuetenango, Guatemala, in 2016. From left to right: Pedro Bello (UC Davis), Esvin López (local collaborator), Denise Costich, José Luis Galicia (Buena Milpa), Ariel Rivers (CIMMYT) and Miriam Yaneth Ramos (Buena Milpa).
Costich with the winners of the Second Harvest Fair and Largest Mature Ear of Jala Maize Contest in Coapa, in Mexico’s Nayarit state.
Costich (left) measures ears of corn for the Second Harvest Fair and Largest Mature Ear of Jala Maize Contest in Coapa, in Mexico’s Nayarit state in 2019.
Costich (center) shares some comments from the stage at the Second Harvest Fair and Largest Mature Ear of Jala Maize Contest in Coapa, in Mexico’s Nayarit state. To her left is Angel Perez, a participating farmer from La Cofradía, and to her right, Rafael Mier, Director of the Fundación Tortillas de Maíz Mexicana.
A bank for farmers
However, according to Zavala, because of the limited knowledge of much material they were working with, many in the bank’s rank-and-file didn’t fully understand the importance of their work. Morale was mixed. Moreover, despite an assumption that her new job would see her working closely with local smallholders, Costich found that the institution was poorly known by everyday farmers in its host country. Where it was known, associate scientist on innovation and social inclusion, Carolina Camacho, notes, there was an assumption that CIMMYT only worked with hybrid varieties of maize and not the native landraces many smallholders in Mexico depend on.
These became the principal axes of Costich’s work at the bank: curation of backlogged material, staff development, and community outreach.
Thus, when Costich realized that records were being kept in a combination of paper and rudimentary digital formats, she sent Zavala, a promising young research assistant at the time, to an internship at the USDA’s Maize Germplasm Bank Collection in Ames, Iowa, to workshops at CGIAR germplasm banks in Colombia (CIAT) and Ethiopia (ILRI), and to meetings on specialized topics in Germany and Portugal.
Zavala had never left the country before, spoke little English, and remembers being “rebellious” at work. “I needed more responsibility,” he says. “Dr. Denise saw that and helped me grow.” Upon returning from an early trip, Zavala helped implement up-to-date traceability and data management processes, including migrating the genebank’s data onto the USDA’s GRIN-Global platform.
But as Payne points out, Costich’s tenure was never about simple bean — or, in this case, grain — counting. “She sees a more human aspect of the importance of the collections,” he says. The main tasks she set for the bank came to be subsumed into the overarching goal of a fuller understanding of the contents of the bank’s vaults, one that encompassed both their biological and sociocultural importance.
When Costich came across a collection of maize landraces from Morelos state assembled by Ángel Kato in the mid 1960s that conserved the name of the farmer who had donated each sample, she worked with Camacho and graduate student Denisse McLean-Rodriguez to design a study involving the donor families and their communities. McLean-Rodriguez, Camacho and Costich set out to compare the effects of ex-situ versus in-situ landrace conservation in both genetic and socioeconomic terms.
Similarly, when a colleague at INIFAP invited Costich to be a judge at a yearly contest for largest ear of Jala landrace maize in Mexico’s Nayarit state, they soon began discussing how they could contribute more than just their participation as judges to the community. Starting in 2016 Costich was a co-lead on a study of the landrace’s genetic diversity as well as an initiative to rematriate Jala seeds conserved at CIMMYT for over 60 years.
Costich and members of the Maize Collection team hosting Pedro Bello from UC Davis (center, glasses) at the CIMMYT Germplasm Bank in Texcoco, Mexico, for a workshop on seed longevity and conservation techniques.
A genebank is not an island
Genebanks are bulwarks against genetic erosion. But, as Camacho explains, this mission can be understood in both very narrow and very broad senses. The narrow sense focuses on genetic processes per se: the loss of alleles. The broad sense includes the loss of cultural practices and knowledge built and sustained around the cultivation of a given landrace. Through the initiatives the bank has undertaken during her tenure, Costich has tried to demonstrate, both scientifically and in practice, how germplasm collections such as CIMMYT’s can complement, reinforce, and be enriched by the work of smallholders — de facto germplasm conservators in their own right — while contributing to the difficult task of combating genetic erosion in the broad sense.
One gets the sense that in Costich’s view this isn’t about a one-way process of big institutions “helping” smallholders. Rather it’s about collaboration among all the participants in an interdependent web of conservation. As she argued at her recent exit seminar, Costich views germplasm banks as one link in a chain of food security backups that begins at the farm level.
Indeed, Costich’s most recent initiative demonstrated how innovations intended for one link in the chain can travel upwards and find applications at bigger institutions.
Costich recently led an initiative with community seed banks in the Cuchumatanes mountain range of Guatemala to study the use of DryChain technology in post-harvest storage of maize. This experiment showed the enormous benefits that incorporating such technologies could yield for energy-insecure or low-tech family and community seed reserves.
Ultimately, however, the study led to a second experiment at CIMMYT’s tropical-climate station at Agua Fría in Mexico. With advice from collaborators at UC Davis and an industry partner (Dry Chain America), the seed conditioning team retrofitted an old drying cabinet at the station to dry maize without using heat, but rather by forcing air to circulate through sacks of drying beads. Under the direction of Filippo Guzzon, a postdoc and seed biologist working with Costich, the long-term viability of seeds dried using the accelerated technique versus traditional, slower techniques was tested. The study showed no loss in long-term viability using the accelerated drying technique.
Denise Costich, CIMMYT director general Martin Kropff, and the Maize Collection team confer certificates of participation to two visiting interns, Jiang Li (to the left of Kropff), a doctoral student from CAAS, Beijing, China, and Afeez Saka Opeyemi (to the right of Costich), a staff member of the IITA Germplasm Bank in Nigeria.
Costich and the Maize Collection team at the 2018 CIMMYT Christmas party. Filippo Guzzon, seated to the right of Costich, had just been offered a postdoc with the team.
Costich and the Maize Collection team at the 2018 CIMMYT Christmas party.
A very busy retirement
At her exit seminar, Costich was presented a plaque in appreciation of her service at CIMMYT by Kevin Pixley, director of the genetic resources program. Terence Molnar, maize breeder with the Genetic Resources Team, has succeeded Costich as the Maize Germplasm Bank Head.
For some of her close colleagues, however, Costich’s departure is not the end of the road. “This is not a forever goodbye,” Guzzon says. “I will continue to be in touch with my cuatita,” says Camacho, who has also left CIMMYT.
For her part, Costich echoes that this is not a forever goodbye at all. Not to her friends and colleagues, and certainly not to her work. At a socially-distanced, maize-based farewell lunch Costich held just days before her departure, she was still busy weaving social connections and furthering collaborations among maize fanatics of all stripes — from chefs and designers to scientists and policy advocates.
She is already considering taking a part time position at her old lab at Cornell and a return to Tripsacum research. At the same time, she will be a visiting scientist at Mexico’s National Center for Genetic Resources (CNRG), where officially she will be heading up part of an international switchgrass study. Costich is hoping to leverage her tenure at CIMMYT by getting involved in a push to help improve the Mexican national system for plant genetic resources. Additionally, she has recently accepted an invitation from Seed Savers Exchange to join their board and she is looking forward to volunteering her time and expertise to various seed-saving initiatives within that organization and their many collaborators.
Asked what she’s looking forward to tackling in her retirement that isn’t work related, Costich betrays her deep allegiance to the plant world. “I don’t know,” she says, “I’m thinking of starting a big vegetable garden.”
Cover photo: Denise Costich stands for a photo during the inauguration of the CIMMYT Genebank museum in 2019. (Photo: Alfonso Cortés/CIMMYT)
The Heat and Drought Wheat Improvement Consortium (HeDWIC) is a global research and capacity building network that takes wheat research from the theoretical to the practical by incorporating the best science into real-life breeding scenarios.
By harnessing the latest technologies in crop physiology, genetics and breeding, HeDWIC makes it easier for wheat scientists to work together on solutions to the complex problems of heat and drought adaptation, contributing to the development of new, climate-resilient wheat varieties for farmers. HeDWIC-associated scientists examine current breeding material and collections held in germplasm banks and apply genomic and phenomic tools to identify novel diversity for heat, drought adaptative traits. This results in novel pre-bred lines in terms of genetic diversity for key stress-adaptive traits suitable for use in breeding programs and/or re-selection as cultivars.
The consortium delivers these lines to public and private wheat programs worldwide via the International Wheat Improvement Network (IWIN) — coordinated for more than half a century by the International Maize and Wheat Improvement Center (CIMMYT) — as international public goods whose global impacts are well documented. Through PhD sponsorships and other opportunities for involvement in research, HeDWIC also provides hands-on training to young scientists, preparing a new generation of crop experts to tackle the pressing issues of crop adaptation under future climate scenarios.
HeDWIC adds value to developing more climate-resilient wheat varieties by:
Facilitating global coordination of wheat research related to heat and drought stress in partnership with the Wheat Initiative.
Developing research and breeding technologies in response to the priorities of stakeholders: researchers, breeders, farmers, seed companies, national programs, and funding organizations.
Connecting geographically and agro-climatically diverse sites for rigorous testing of promising concepts.
Curating data resources for use by the global wheat research community.
Accelerating the deployment of new knowledge and strategies for developing more climate resilient wheat.
Preparing a new generation of promising young scientists from climate-affected regions to tackle crop improvement challenges faced by their own countries.
Building additional scientific capacity of wheat researchers in a coordinated fashion that enables a faster response to productivity threats associated with climate change.
Enabling farmers to adapt to wheat production in a hotter and drier climate faster due to the coordinated effort and synergy lent by HeDWIC.
HeDWIC is directly funded by the Foundation for Food and Agriculture Research (FFAR) and is supported by in-kind contributions from IWIN, the Bill & Melinda Gates Foundation/UK Foreign, Commonwealth and Development Office (FCDO)-funded Accelerating Genetic Gains in Maize and Wheat for Improved Livelihoods (AGG) project, the CGIAR Research Program on Wheat (WHEAT), the International Wheat Yield Partnership, the Wheat Initiative’s AHEAD, and many international partners who support research and capacity building activities through ongoing collaboration.
It also builds on decades of breeding and collaborative research under abiotic stress coordinated by CIMMYT, with support from agencies including Mexico’s Secretariat of Agriculture and Rural Development (SADER), the CGIAR Trust Fund —in particular the Australian Centre for International Agricultural Research (ACIAR), the UK Foreign, Commonwealth and Development Office (FCDO), and the US Agency for International Development (USAID) — Australia’s Grains Research Development Corporation (GRDC), Germany’s Ministry of Agriculture (BMEL), the Bill & Melinda Gates Foundation, the US Department of Agriculture (USDA), and others.
The challenges facing our food system are growing, both in size and in complexity. In order to tackle these issues and meet the needs of our changing world, the International Maize and Wheat Improvement Center (CIMMYT) understands the importance of assembling a workforce that is diverse, creative and representative. In addition to encouraging STEM careers and hiring more women in scientific positions, we must also foster a more encouraging scientific community for women whose careers are just sparking.
Whether it is through a school field trip, a first internship or a PhD thesis project, CIMMYT is committed to encouraging young women to step into the lab and the fields, and up to the challenge, as we strive to create a more equitable community. On the International Day of Women and Girls in Science, we are inspired by the words of some of the many brilliant women whose scientific careers are just beginning, lighting the pathway to a more equitable future.
The International Day of Women and Girls in Science is particularly meaningful to CIMMYT’s new Global Wheat Program (GWP) Director, Alison Bentley. Listen and watch as she tells her story, from her first lightbulb moment on a high school field trip, to a leadership position in the wheat research world.
In celebration of the International Day of Women and Girls in Science, CIMMYT is participating in a unique marathon event, carrying a global conversation with CGIAR women scientists that are leading change and creating solutions to some of the world’s biggest challenges.
Powered by Women in Research and Science (WIRES), a new employee-led resource group at CGIAR, the event will showcase the many ways women scientists are transforming the way we look at our food, land and water systems around the world. In addition to learning about cutting-edge science, you’ll be able to engage with inspiring speakers in 13 different countries.
Join CIMMYT’s discussion on February 11, 2021, at 1:00 p.m. CST, and learn about the journeys of the 2020 Bänziger Award recipients, an engaging Q&A with four CIMMYT scientists, and our vision for a more equitable workforce. Register for the event.
Global thought leader, philanthropist and one of the International Maize and Wheat Improvement Center (CIMMYT) and CGIAR’s most vocal and generous supporters, Bill Gates, wrote a book about climate change and is now taking it around the world on a virtual book tour to share a message of urgency and hope.
