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Pillar: Discovery

Fungal Resistance in Wheat: Biodiversity & Food Security

CIMMYT played a key role in advancing research on yellow rust resistance by supporting field trials in Mexico and providing access to its extensive collection of traditional wheat varieties. Through its collaboration with the University of Zurich and Kyoto University, CIMMYT contributed to the identification of novel genetic regions in Asian landraces that offer resistance to the destructive fungus. Its leadership in conserving one of the world’s largest wheat germplasm collections continues to be vital for global efforts to develop disease-resilient wheat and safeguard food security through biodiversity.

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Pairwise Licenses Gene Editing Tools to CIMMYT to Fast-Track Smallholder Farming Systems’ Transformation

Durham, N.C., and Texcoco, Mexico (June 12, 2025) – Pairwise has entered a landmark licensing agreement with the non-profit, international agricultural research organization CIMMYT to provide access to its Fulcrum™ gene editing platform, including the advanced SHARC™ CRISPR enzyme. This partnership will accelerate the development of improved crop varieties for smallholder farmers across 20 countries where CIMMYT implements integrated research and development initiatives.

CIMMYT, based in Mexico and operating in 88 countries, is a key member of the CGIAR network and a global leader in developing sustainable solutions for food and climate security. Under the license, CIMMYT and its National Agricultural Research Systems (NARS) partners will have access to Fulcrum tools in crops including maize, wheat, sorghum, and regionally important staples like pearl millet, finger millet, pigeon pea, and groundnut.

“Advanced breeding techniques replicate what happens in nature in a faster, more focused way. We’re excited to have access to a gene editing technology that allows us to not only develop new traits but also make these traits available to farmers who can benefit from them,” said Sarah Hearne, Chief Science and Innovation Officer at CIMMYT. “CIMMYT is committed to bringing new technologies to smallholder farmers in the Global South, which aims to enhance resilience and nutritional characteristics of crops and help develop livelihoods and communities. Fulcrum will speed up the delivery of the climate resilient varieties that farmers urgently need.”

The Fulcrum™ Platform includes Pairwise-developed gene editing tools for cutting, base editing, and templated editing a toolbox which enables not only turning a characteristic on or off but also tuning it— like a dimmer switch to tailor the trait and deliver the optimum phenotype.

“Our Fulcrum Platform was built to help scientists solve urgent, real-world challenges in agriculture,” said Ian Miller, Chief Operating Officer at Pairwise. “This agreement allows CIMMYT to use our powerful CRISPR tools to deliver real-world improvements for farmers facing food insecurity and climate pressure. We outlicense to organizations like CIMMYT because Pairwise believes this transformative technology should be broadly available to those working to improve agriculture for smallholder farmers.”

Gene editing enables precision improvements in crop yield, resilience, and nutrition that could be achieved through conventional breeding but were impractical due to time and cost restraints.  By making these powerful tools more accessible, this partnership accelerates impactful innovation in regions where food system improvements are most urgently needed. Through CIMMYT’s research network, these tools will be deployed in diverse environments, providing researchers with a flexible alternative for product development and a clear pathway to real-world impact.

About Pairwise
Pairwise is agriculture’s leading gene editing powerhouse, building a healthier world through partnership and plant innovation. Co-founded by the inventors of CRISPR, our Fulcrum™ Platform accelerates the development of climate-resilient, nutritious, and sustainable crops. As trusted partners to global industry leaders and nonprofit institutions, we help breeders move faster while transforming food and agriculture for farmers, consumers, and the planet. Founded in 2017 and based in Durham, NC, Pairwise is committed to delivering innovation that makes food easier to grow — and better to eat. For more information, visit www.pairwise.com.

About CIMMYT
CIMMYT is a cutting-edge, non-profit, international organization dedicated to solving tomorrow’s problems today. It is entrusted with fostering improved quantity, quality, and dependability of production systems and basic cereals such as maize, wheat, triticale, sorghum, millets, and associated crops through applied agricultural science, particularly in the Global South, through building strong partnerships. This combination enhances the livelihood trajectories and resilience of millions of resource-poor farmers while working towards a more productive, inclusive, and resilient agrifood system within planetary boundaries.
www.cimmyt.org

 

CIMMYT Media Contact: Jelle Boone
Head of Communications, CIMMYT
Email: j.boone@cgiar.org
Mobile: +52 595 124 7241

Pairwise Media Contact:
Email: communications@pairwise.com

Fingerprinting bioinformatics pipeline cuts seed purity testing from days to clicks

A new bioinformatics-driven tool dramatically accelerates seed purity testing, offering fast, automated parental purity checks and hybridity verification—thereby increasing the effectiveness of breeders, seed companies, and regulators.

Waiting days—or even weeks—to analyze Single Nucleotide Polymorphism (SNP) assay data to verify the genetic purity and hybridity of seeds and crosses may soon be a thing of the past. A new bioinformatics-driven seed purity testing pipeline significantly reduces the time required to confirm seed identity, bringing it down to just a few clicks.

The new pipeline uses DNA fingerprinting with SNPs in a fast, accurate, and scalable automated genetic analysis.

Modernizing Genetic Purity and Hybridity Testing

Traditionally, seed producers and certification agencies have relied on grow-out tests and morphological analysis to assess genetic purity. These methods are labor-intensive and time-consuming, often requiring weeks or months of field or greenhouse work by trained technicians.

Although CIMMYT has long used molecular markers to verify parental purity and hybridity, challenges remained—particularly the lack of automated tools and integrated platforms to make the process seamless and accessible.

That is changing, thanks to software developed by Abhishek Rathore and team. The pipeline automatically compares each sample’s genetic profile to its expected reference using a custom algorithm. Based on user-defined thresholds, the tool confirms parental purity, identifies putative F1 hybrids, and flags failed crosses.

“We wanted a tool that breeders and seed companies can use without needing specialized bioinformatics skills,” said Abhishek Rathore, bioinformatics specialist at CIMMYT. “Once the DNA data is generated, the analysis is push-button. The software quickly interprets the SNP results and produces an easy-to-read report on seed purity. It’s about making advanced bioinformatics accessible and routine for parental purity and F1 verifications.”

Speedy, Automated, and User-Friendly

Early implementation of the pipeline has demonstrated large gains in speed and efficiency. What previously required extensive manual effort can now be completed in minutes.

The system is designed with user-friendliness in mind: lab technicians simply upload SNP assay results into an intuitive interface, and the pipeline returns clear metrics—such as “% purity”—while flagging any off-type individuals. With the computational workload fully automated, even seed companies and labs with minimal informatics infrastructure can benefit.

“Automation is key,” added Rathore. “By reducing manual steps and subjective interpretation, we save time and minimize human error. You can process dozens of seed samples overnight and receive a comprehensive genetic report by morning.”

To make this automation accessible to stakeholders across NARS, CIMMYT’s biometrician Roma Das developed a user-friendly web interface, while Peter Kimathi, a bioinformatics and software developer, developed a custom report and deployed the pipeline as a web service on CIMMYT’s servers (link below).

Widespread Adoption Across Africa

Since its rollout, the pipeline has been widely adopted by CIMMYT and partners through the Africa Dryland Crops Improvement Network (ADCIN). Mohan Chejerla, Genomics Expert at CIMMYT, has already applied the pipeline to over 23,000 samples, ensuring quality assurance and quality control (QA/QC) for breeding pipelines across Kenya, Uganda, Mali, Senegal, Burkina Faso, Ethiopia, Tanzania, Niger, Togo, Zambia, and Ghana.

This broad uptake underscores the demand for reliable, scalable seed purity testing—and the pipeline’s value for enhancing crop breeding and seed system integrity.

Additional Information:
🔗 Pipeline Source Code
🔗 CIMMYT Pipeline Implementation

Evangelina Villegas: A Pioneer Woman in Agricultural Science, Inspired by Norman Borlaug

Norman Borlaug was awarded the Nobel Peace Prize in 1970 for leading an agricultural revolution in Mexico, specifically in the Yaqui Valley in Sonora, where he developed high-yield, disease-resistant wheat varieties that helped save the lives of thousands threatened by hunger.

Evangelina Villegas, together with Dr. Surinder Vasal (left) and Norman Borlaug (second from right), share a moment together. (Photo: CIMMYT)

His legacy, driven by CIMMYT in collaboration with the Government of Mexico, has had a profound and lasting impact on global food security. This legacy has inspired and empowered the role of numerous women in agricultural science, encouraging them to lead innovative and essential research to address global food challenges. 

Among the women who have stood out due to this influence is Evangelina Villegas, a Mexican scientist whose pioneering work in nutritional maize improvement had a global impact. Together with Dr. Surinder Vasal, Villegas developed quality protein maize (QPM), an innovation that significantly reduced malnutrition and improved nutritional quality for millions of people in developing countries. For these contributions, Evangelina Villegas was awarded the World Food Prize in 2000, becoming the first woman to receive this prestigious honor. 

Beyond her scientific achievements, Evangelina Villegas stood out for her commitment to mentoring new generations of researchers, especially women. Her efforts opened doors for more women scientists to participate in high-impact social projects, establishing her as a role model for female leadership in agricultural science. 

Villegas’s career clearly reflects the continuation of the social and scientific commitment initiated by Borlaug. Her example highlights how his legacy has not only positively influenced science but also played a crucial role in advancing gender equity within the agricultural and scientific sectors. 

An award presented to Evangelina Villegas for the 2000 World Food Prize, recognizing her contribution to global food security. (Photo: Jenifer Morales/CIMMYT)

Today, the life and work of Evangelina Villegas continue to inspire young women researchers, demonstrating how fostering female leadership in agriculture is essential for building sustainable, inclusive, and equitable food systems capable of addressing current and future challenges. 

Evangelina Villegas in her laboratory conducting analyses that led to the development of quality protein maize (QPM). (Photo: CIMMYT)

New Breakthrough in Wheat Blast Resistance: A Novel Non-2NS QTL Identified

A newly published study has identified a significant breakthrough in the ongoing battle against wheat blast: a novel quantitative trait locus (QTL), named Qwb.cim-7D, located on the long arm of chromosome 7D and derived from Aegilops tauschii, offers stable and moderate resistance to wheat blast—independently of the widely used 2NS translocation.

Wheat blast, caused by Magnaporthe oryzae pathotype Triticum (MoT), is a rapidly spreading disease threatening wheat production, particularly in tropical and subtropical regions of the world. First detected in Brazil in 1985, the disease has since caused devastating yield losses—up to 100% in severe cases. Its transboundary spread, including recent incursions in Bangladesh and Zambia, has intensified international concerns about food security, especially among vulnerable smallholder farming communities. Control through chemical means has proven unreliable, placing even greater emphasis on the development and deployment of resistant wheat cultivars.

Fig. 1 Global incidence of wheat blast with years of its first identification indicated for the affected countries

For years, wheat breeders have relied on a single major source of genetic resistance—the 2NS/2AS translocation from Aegilops ventricosa. While initially effective, recent field observations—particularly in Brazil—suggest that wheat blast pathogens are evolving to overcome this resistance. Despite extensive efforts, previous studies have failed to identify any non-2NS QTLs with both significant and stable effects across environments in field trials.

Fig. 2 Contrasted wheat blast reactions between BWMRI Gom 3 (left, a 2NS carrier) and BARI Gom 26 (right, a non-2NS carrier)

A New Genetic Solution for Blast Resistance

In a recently published study entitled “A novel QTL on chromosome 7D derived from Aegilops tauschii confers moderate field resistance to wheat blast”, CIMMYT’s wheat pathology team and collaborators reported the identification of a novel and consistent QTL—Qwb.cim-7D—which provides significant resistance to wheat blast independent of the 2NS translocation.

The donor bread wheat line, Gladius*2/KU 2097, inherited its resistance from the resistant Ae. tauschii accession ‘KU-2097’. Field experiments were conducted at two Precision Phenotyping Platforms (PPP) in Bolivia (Quirusillas and Okinawa) and one PPP in Bangladesh (Jashore), under artificially inoculated conditions—ensuring a robust evaluation of resistance. The QTL was mapped to the long arm of chromosome 7D, where it explained between 7.7% and 50.6% of the phenotypic variation across different environments. This is a significant finding, as previous studies identified non-2NS resistance loci with typically small effects (less than 10%) and inconsistent performance. In contrast, Qwb.cim-7D is the first moderate-effect QTL to demonstrate stable resistance across multiple field conditions.

To facilitate its adoption in breeding pipelines, researchers successfully converted the flanking DArTseq markers into KASP markers—enabling more efficient marker-assisted selection.

Importantly, Qwb.cim-7D provides approximately half the resistance effect of 2NS, highlighting its value as a complementary resistance factor. When deployed through gene pyramiding strategies alongside 2NS and Rmg8, this new QTL could help breeders develop varieties with stronger and more durable resistance to the evolving wheat blast pathogen.

This breakthrough marks a turning point in global wheat blast resistance breeding. It addresses the urgent need to diversify the genetic basis of resistance and equips breeders with a viable new tool to safeguard wheat yields. As wheat blast continues to threaten food security in key regions, the introgression of Qwb.cim-7D into breeding programs offers a promising path toward enhanced crop resilience and improved farmer protection.

Seven New CIMMYT maize hybrids available from Eastern Africa Breeding Program

CIMMYT is happy to announce seven new, improved tropical maize hybrids that are now available for uptake by public and private sector partners, especially those interested in marketing or disseminating hybrid maize seed across Eastern Africa and similar agro-ecologies in other regions. NARES and seed companies are hereby invited to apply for licenses to pursue national release, scale-up seed production, and deliver these maize hybrids to farming communities.

Newly available CIMMYT hybrids Key traits
CIM23EAPP1-01-07 Intermediate maturing, white, high yielding, drought tolerant, NUE, and resistant to GLS, TLB, MSV, ear rots, and root & stalk lodging tolerance.
CIM23EAPP1-02-12 Early maturing, white, high yielding, drought tolerant, NUE, and resistant to MLN, MSV, GLS, TLB, ear rots, and root & stalk lodging tolerance
CIM23EAPP1-02-13
CIM23EAPP1-02-15
CIM23EAPP2-15 Late maturing, white, high yielding, drought tolerant, NUE, and resistant to MSV, GLS, TLB, rust, ear rots, and root & stalk lodging tolerance
CIM23EAPP3-40 Late-maturing, high-yielding, white maize hybrids adapted to high altitudes, with resistance to GLS, TLB, rust, and ear rots.
CIM23EAPP3-42

 

Performance data Download the Seven New CIMMYT maize hybrids available from Eastern Africa Breeding Program from Dataverse.
How to apply Visit CIMMYT’s maize product allocation page for details
Application deadline The deadline for submitting applications to be considered during the first round of allocations is 14 May 2025. Applications received after that deadline will be considered during subsequent rounds of product allocations.

 

The newly available CIMMYT maize hybrids were identified through rigorous, years-long trialing and a stage-gate advancement process which culminated in the Results of the CIMMYT Eastern Africa Maize Regional On-Station (2023 Stage 4) and On-Farm (2024 Stage 5) Trials On-Farm Trials. The products were found to meet the stringent performance and farmer acceptance criteria for CIMMYT’s breeding pipelines that are designed to generate products tailored in particular for smallholder farmers in stress-prone agro-ecologies of Eastern Africa.

Applications must be accompanied by a proposed commercialization plan for each product being requested. Applications may be submitted online via the CIMMYT Maize Licensing Portal and will be reviewed in accordance with CIMMYT’s Principles and Procedures for Acquisition and use of CIMMYT maize hybrids and OPVs for commercialization. Specific questions or issues faced with regard to the application process may be addressed to GMP-CIMMYT@cgiar.org with copy to Michael Nyagowa (m.omondi@cgiar.org), Program Assistant – Seed Systems & Technology Transfer, Global Maize Program, CIMMYT.

 

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Sugar Signalling Breakthrough Could Increase Wheat Yields by Up to 12%

Extensive multi-year field trials conducted by CIMMYT in Mexico played a pivotal role in validating the efficacy of the Trehalose 6-phosphate (T6P) spray treatment, confirming its potential to boost wheat yields by up to 12%. Despite challenges posed by fluctuating rainfall—an increasingly common constraint under climate change—CIMMYT’s trial plots consistently outperformed untreated controls across four consecutive crop cycles. These results underscore CIMMYT’s leadership in translating laboratory innovations into resilient, field-ready solutions that enhance food security while advancing sustainable agrifood systems in diverse agroecological conditions.

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CIMMYT Appoints Flavio Breseghello as Global Wheat Program Director

(Photo: CIMMYT)

CIMMYT is pleased to announce the appointment of Flavio Breseghello as the new Director of the Global Wheat Program. A renowned wheat breeder and leader in agricultural research, Breseghello will guide CIMMYT’s flagship wheat initiative at a pivotal moment for global food security. 

“CIMMYT’s wheat program has long been a cornerstone of global food security,” said Breseghello. “I’m honored to contribute to this legacy, while helping shape its future in the face of new challenges.” 

With over two decades of experience advancing wheat research in Brazil and internationally, Breseghello brings scientific expertise and strategic vision to the role. His appointment underscores CIMMYT’s commitment to science-driven innovation that responds to evolving global needs—particularly in low- and middle-income countries where wheat is a staple crop and climate resilience is increasingly urgent. 

“Climate change is reshaping the risks and realities for wheat farmers in low- and middle-income countries,” Breseghello said. “Our challenge—together with our partners—is to stay ahead of these threats with science that is inclusive, adaptive, and driven by the needs of the most vulnerable.” 

CIMMYT’s Global Wheat Program is at the forefront of developing high-yielding, climate-resilient, and disease-resistant wheat varieties that feed over 2.5 billion people around the world. As director, Breseghello will lead efforts to strengthen international research collaboration, expand capacity building, and ensure the program’s innovations reach those who need them most. 

“Flavio is a globally respected leader whose deep experience and inclusive approach will be a tremendous asset to the program and to the global wheat community,” said Bram Govaerts, Director General of CIMMYT. “We are thrilled to welcome him to this vital role.” 

Shaping a CIMMYT maize program to serve at-risk farmers: A tribute to Ernest W. Sprague (1925-2025)

Photo caption: Ernest W. Sprague, director of CIMMYT’s maize program during 1970-1983 (Photo: CIMMYT)

Architect of CIMMYT maize research during the 1970s, Ernest W. Sprague pulled together a coherent global program from diverse regional and country initiatives in Latin America, Asia, and eastern Africa, building partnerships with national maize research programs to serve smallholder farmers.

On 25 February, Ernest W. Sprague, who served as Maize Program Director at CIMMYT from 1970 to 1983, passed away at the age of 100.

Sprague led the development and adoption of systematic approaches for breeding improved maize populations adapted to the tropics and subtropics, including the international testing of varieties and crosses at scale.

After leading the Inter-Asian Corn Program established by the Rockefeller Foundation in Thailand in 1966, Sprague joined CIMMYT, where he vigorously championed the role of open-pollinated maize varieties (OPVs) for smallholder farmers in rain-fed maize cropping areas. These farmers often faced diseases, pests, and drought and lacked access to or could not afford hybrid seed or large quantities of fertilizer.

OPVs generally yield less grain than maize hybrids but are often preferred by smallholders for their suitability in local foods. They can also be grown by saving and sowing seed from previous harvests without sacrificing yield or other qualities—a problem that arises when grain harvested from hybrids is replanted.

In Thailand, Sprague had witnessed a thriving maize sector powered by the widespread adoption of an improved OPV known as “Suwan 1.” Conversely, he believed that hybrid seed systems designed to serve small-scale farmers were lagging in many other countries where CIMMYT worked.

“From the late 1980s, CIMMYT has worked successfully to develop and share hundreds of maize inbred lines—parents for high-yielding hybrids that feature farmer-preferred traits—as well as supporting and partnering with competitive private seed sector companies that truly benefit smallholder maize farmers,” said Bram Govaerts, CIMMYT Director General. “Still, population improvement in the OPV breeding program under Sprague’s leadership clearly contributed to the success of CIMMYT’s hybrid research by increasing the average performance of lines extracted from those populations.”

In addition, much of CIMMYT’s research on hybrid breeding for tropical maize in the 1980s and 1990s was led by Surinder K. Vasal, an Indian maize scientist brought to CIMMYT by Sprague.

Vasal’s pre-biotech research, together with CIMMYT cereal chemist Evangelina Villegas, led to the development of quality protein maize (QPM), whose grain contains enhanced levels of two amino acids essential for human protein synthesis. This groundbreaking work—initiated by Sprague—was recognized with their joint reception of the 2000 World Food Prize.

Building up partners and partnerships

Sprague was a strong proponent of in-service training at CIMMYT headquarters in Mexico for young researchers from partner countries. These courses were formally organized and scaled up in the early 1970s as a major component of CIMMYT’s maize program. Participants worked for several months within the main breeding or production programs, usually in the lowland tropics of Mexico, gaining hands-on skills in the field through activities such as laying out on-farm trials, selecting germplasm, making crosses, and evaluating results. By 1982, the program had graduated 650 maize scientists from 61 countries. Many alumni rose to influential positions in national programs or the private sector, thereby strengthening regional cooperative maize research networks.

“Ernie was my boss when I first arrived as a postdoc to CIMMYT in 1976, and I was always amazed at his commitment to high-quality field work,” said Greg Edmeades, a maize physiologist whose research accomplishments included methods to select for drought tolerance in maize. “I will always remember Ernie as a friend and a great supporter of the task we faced in Ghana, where I worked as a maize agronomist and lived with my family during 1979–84. He thought often of the challenges that we as a family faced with frequent water and power cuts and generously provided support. I was always amazed at his stamina and his capacity to survive and keep fit and well on black coffee alone in the mornings and no major meal until evening.

“Sprague’s contributions to CIMMYT were significant. The setting up of the international testing system was his baby and a masterpiece in getting CIMMYT germplasm out to national programs. He elevated the status of national programs in all sorts of ways, not the least of which was training.”

The CIMMYT global community joins in remembering Ernie Sprague and extends heartfelt condolences to his family.

The International Wheat Yield Partnership (IWYP) announces new program director

The International Wheat Yield Partnership (IWYP) and the Biotechnology and Biological Sciences Research Council (BBSRC) of the UK are pleased to announce the appointment of Dr Jeff Rosichan as Program Director of IWYP, following the retirement of Jeff Gwyn last year.

Dr. Rosichan joins IWYP after 30 years as an R&D leader in both the private and public sectors. During that time, he led complex multinational, multidisciplinary and multifunctional research teams. Most recently he was Scientific Program Director for the Foundation for Food and Agriculture Research (FFAR) where he was the Director for the Crops of the Future Consortium and Next Generation Crops Challenge Area. He will continue to reside in the USA.

BBSRC has provided the consultancy position in recognition of the valuable achievements of IWYP in serving the wheat scientific community over these past 10 years during which IWYP has been funded and guided by numerous governmental funding agencies and private sector wheat breeding companies.

IWYP’s strong links are with scientists studying yield-related wheat traits all over the world as well as with many breeding programs, public and private. IWYP’s mission is to serve breeding programs, especially through its Hubs in CIMMYT, Mexico, Kansas State University in the USA and the National Institute of Agricultural Botany in the UK, by delivering trait-improved elite germplasm.

More information can be found at IWYP.ORG

Innovation and Partnerships for a Food, Nutrition, and Climate-Secure Future

Every two years, CIMMYT hosts its Science and Innovation Week (SIW), a moment not only for reflection but also for action. SIW2025 is more than a gathering; it is a call to action, challenging us to create lasting change and transformative impact. Each day, we wake up with a bold mission: to make our work meaningful to the ultimate beneficiaries – smallholder farmers.

To kick off this year’s Science Week, CIMMYT Director General Bram Govaerts reminded participants that at the heart of our work is real-world impact. More than an opportunity to evaluate strategies, Science Week is about envisioning and driving the future of food systems.

“CIMMYT’s work connects communities worldwide, from labs to corn harvests. Your tireless research deserves accolades as profound as a Nobel Prize” said Ted McKinney, CEO of the JS National Association of State Departments of agriculture, NASDA & Former USDA Undersecretary. Recognizing this urgency, CIMMYT convened leading scientists, researchers, and decision-makers at its headquarters in Texcoco, Mexico, for Science Week 2025.

This flagship event brought together experts at the intersection of agriculture, climate and food security to foster collaboration and inspire action for resilient food systems. With CIMMYT’s research agenda focused on addressing the world’s most pressing agricultural challenges, Science Week served as a key platform to shape the future of innovation, strengthen partnerships, and accelerate impact on global food security. Through knowledge sharing and strategic discussions, participants explored transformative solutions that will empower smallholder farmers, build crop resilience, and ensure a sustainable future for food systems worldwide.

A platform for collaboration and innovation

The first day set the stage for a dynamic exchange of ideas, bringing together global experts to address agriculture’s most pressing challenges. Discussions explored climate-smart agriculture, the role of digital transformation, and the resilience of seed systems, highlighting the need for innovation to ensure food security. Advances in crop breeding and cutting-edge research took center stage, reinforcing CIMMYT’s commitment to developing scalable, science-based solutions that empower farmers.

Sessions covered a wide range of topics, including climate-smart agriculture, digital transformation in agriculture, resilience of seed systems, and advances in crop breeding. High-level panels and thought leaders highlighted the importance of collaboration, from integrating AI and strategic partnerships to amplifying research impact, while deep diving into CIMMYT’s scientific breakthroughs. The challenge was clear: think beyond the event, push boundaries, and make a meaningful impact that extends far beyond this week.

From data-driven decision-making to sustainable food production, discussions reinforced the need for strategic collaboration, digital transformation, and responsible innovation. With a strong focus on open data and climate resilience, day two underscored CIMMYT’s commitment to translating science into real-world impact for farmers and food systems worldwide.

With CIMMYT generating around 122 datasets annually, experts stressed the importance of improving data quality, integrating new information, and standardizing workflows for greater transparency and efficiency. The discussions also tackled food security, conflict, and economic instability. With 8.4 million people affected by food insecurity in Latin America and the Caribbean, experts highlighted the urgent need for social protection systems, digital solutions, and adaptive policies.

Moving forward, CIMMYT must bridge science and action, ensuring that research translates into tangible solutions for farmers and food systems worldwide – because resilience is not just an option; it is the foundation of sustainable agriculture.

Scientific excellence in action

As Science Week 2025 drew to a close, discussions focused on two key themes: partnerships and communicating impact. To kick off the session, Aaron Maniam, Fellow of Practice and Director, Digital Transformation Education, Oxford University Blavatnik School, challenged participants to rethink collaboration – not just as coordination but as a balance between integration and fragmentation. Collaboration is non-negotiable, and positioning CIMMYT as the partner of choice will be critical to advancing its mission.

Today’s challenges are too complex to tackle alone, and strategic partnerships are essential to amplify impact, leverage resources, and scale innovation. But successful partnerships go beyond collaboration – they require trust and shared goals. Science must be accessible, compelling, and strategically packaged to engage diverse audiences and drive real-world change. As we move forward, the challenge is clear: Embrace, amplify, and boldly communicate our impact to shape the future of food and agriculture. The work does not stop here, this is just the beginning of the next chapter in transforming global food systems for a food and nutrition secure world.

Minister warns of counterfeit seed risks as planting season looms

Uganda’s Dr. Godfrey Asea of NaCRRI was recognized for developing over 20 maize varieties, including drought-tolerant hybrids that support food security. His work has earned multiple breeding and technology awards from CIMMYT, reflecting CIMMYT’s commitment to advancing climate-resilient maize in Africa. As Uganda’s Minister of Agriculture warns against counterfeit seeds, CIMMYT’s efforts in supporting national research institutions remain crucial in ensuring farmers have access to high-quality, stress-tolerant seeds.

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The Guardians of Diversity: The Work of Carolina Sansaloni

Carolina Sansaloni, Curator of the Wheat Collection at the Germplasm Bank and a specialist in genotyping highlights the role of women in preserving agricultural biodiversity and encouraging new generations to pursue their passion for research.

Carolina Sansaloni, genotyping specialist and wheat curator, emphasizes the role of women in science and agricultural conservation. (Photo: Gabriela Bracamonte/CIMMYT)

Since childhood, Carolina Sansaloni has been fascinated by nature and genetics. Her desire to find answers led her down a challenging path, but one that ultimately brought her to where she is today: Curator of the Wheat Collection at CIMMYT’s Germplasm Bank, one of the most important in the world. Her work, and that of her team, is fundamental to food security and nutrition, ensuring the protection and accessibility of wheat and maize genetic diversity to meet the challenges of climate change and growing food demand.

“For me, the greatest satisfaction is knowing that what we do at CIMMYT helps more people put food on their tables. It’s not an individual effort; it’s a collective effort for a greater good,”

But the Germplasm Bank’s impact goes beyond conservation. Its team of scientists, technicians, laboratory staff, and field workers plays a critical role in research and safeguarding one of the world’s most valuable collections of maize and wheat. From seed collection and storage to characterization and distribution for genetic improvement programs, each woman on this team is an essential part of CIMMYT’s mission: generating science and innovation for a food-secure and fed world.

The journey for women in science has not been easy. Sansaloni acknowledges that while she has had mentors and support throughout her career, many women still face challenges in the scientific field.

“A woman’s voice in science has to be earned. We face obstacles, but with perseverance, support, and determination, we can overcome them,” she says.

Leaving her home in Argentina to pursue her passion was one of her biggest challenges. “The biggest challenge was leaving my environment, my family, my friends, but I knew that my motivation was science and its power to change the world.” Today, her story inspires many young women to embrace their curiosity and pursue careers in science.

To girls who dream of science, she says, “Explore, question, discover. With effort and dedication, nothing is impossible.”

To parents, she advises: “Encourage your children’s curiosity, let them make their own choices, and you will be amazed at their ability to innovate.”

We honor all the professionals at CIMMYT, whose knowledge, commitment, and dedication are key to achieving a world of food security and nutrition.

If you’ve ever dreamed of changing the world, science is a great place to start.

Scientific careers that are transforming the future of food for humanity

MarĂ­a Luisa Cabrera in the laboratory where she conducts her research at CIMMYT. (Photo: Francisco AlarcĂłn / CIMMYT)

The progress of science and technology depends on the diversity of talent that contributes to its development. However, the participation of women in fields such as science, technology, engineering, and mathematics (STEM) remains limited. In Mexico, only 22% of women enrolled in higher education choose STEM fields, and according to the Mexican Institute for Competitiveness (IMCO), only 13.5% graduate.

This situation presents both challenges and opportunities. Science, especially in critical areas such as food security and nutrition, needs a greater presence of women to drive significant change. The Food and Agriculture Organization of the United Nations (FAO) has highlighted the urgency of integrating more women researchers into agricultural science to accelerate innovations that improve production and the well-being of rural communities.

One example of the transformative impact of women in science is MarĂ­a Luisa Cabrera Soto. Since childhood, Luisa was inspired by female scientists she saw in the media, which fueled her dream of working in a laboratory. “These women were my reference, my source of inspiration. I visualized myself and said, ‘I want to work in a lab.'” But her journey was not easy. Coming from a family with traditional gender expectations, she faced resistance to her desire to pursue a career in science.

The first obstacle she encountered was her family’s outright disapproval. “I come from a family of six women and a patriarchal figure. Hearing phrases like ‘you are not capable of studying something as complex as science or mathematics’ was the first barrier I had to overcome,” she recalls.
“I had to break these family stigmas, these traditions, and say to myself: ‘I am capable of studying what motivates and inspires me, which is science. Being a woman does not limit me to domestic activities.'”

Today, the girl who once dreamed of working in a laboratory is part of the CIMMYT research team. As a research assistant, her work in chromatography—a process that allows the separation, identification, and quantification of chemical components in various mixtures—helps assess the nutritional quality of various crops, primarily maize. Her work has a direct impact on the nutrition and health of various populations, as well as the livelihoods of agricultural producers.

MarĂ­a Luisa’s story has become an inspiration to her sisters, who have also ventured into the world of science, demonstrating how one personal choice can inspire change across generations. “I broke the paradigm in my family, and fortunately my four younger sisters also chose science. It was a change that broke down a major barrier in my home.”

Through their scientific work, Luisa and other female researchers at CIMMYT are making a significant contribution to improving the human condition in a sector where women play a critical role in food production and security, from the field to the laboratory.

The low percentage of women in STEM fields in Mexico and globally is not only an issue of equity—it is also an obstacle to developing innovative solutions in key sectors. According to UNESCO, only 33.3% of researchers worldwide are women. Luisa’s message to girls and young women in Mexico is clear: “Follow your dreams, question the world, and don’t let social ideologies or family traditions dampen your curiosity and enthusiasm. More and more women are joining this field, and we must support one another.”

Time Running Out to Avert Food Catastrophe, but There Is Hope

Time is of the essence, but we are not making the most of it in the fight against hunger. In 2015, world leaders agreed to set ambitious targets for addressing humanity’s most pressing concerns, which shaped the 2030 Agenda and became widely known as the Sustainable Development Goals (SDGs). We are only five years from 2030, but SDG 2 Zero Hunger has completely slipped through our fingers. In 2023, there were between 713 million and 757 million undernourished people in the world. The latest estimates point to an uncomfortable truth: hunger is on the rise, and we will not meet SDG 2 by the end of this decade.

The outlook is so bleak that 153 Nobel and World Food Prize recipients signed an open letter published on Jan. 14 calling on political and business leaders worldwide to seriously fund “moonshot” efforts to change our current trajectory and meet the food requirements of a global population of 9.7 billion people by 2050. The renowned signatories are sounding the alarm at the dawn of 2025 because it takes decades to reap the rewards of agricultural research and development programs, but also because yields of staple crops are stagnating or even declining around the world at a time when food production should increase between 50% to 70% over the next two decades to meet expected demand.

Joint 2024 World Food Prize Laureate and former U.S. Envoy for Global Food Security Cary Fowler coordinated the global appeal, which was discussed during a hearing with the US Senate Committee on Agriculture in Washington, D.C. The open letter published afterward listed the most promising scientific breakthroughs that should be prioritized to sustainably increase food production, including “improving photosynthesis in staple crops such as wheat and rice to optimize growth; developing cereals that can source nitrogen biologically and grow without fertilizer; as well as boosting research into hardy, nutrition-rich indigenous crops that have been largely overlooked for improvements.”

The good news is that we already have the platform of cutting-edge science to develop and scale up these innovations where they are most needed in Mexico and in nearly 90 countries where CIMMYT works with the support of an unrivalled network of international donors and local partners.

Increasing Wheat’s Ability to Capture, Use Sunlight

Varieties of wheat plants differ in their capacity to use sunlight to produce grain. The main goal of breeders is to increase wheat’s yield potential to harvest more grain sustainably and from the same area of arable land. At present, current breeding can increase wheat’s average yield potential by 1% annually, but it would be necessary to achieve average yield increases of at least 1.7% year after year to meet the expected demand by 2050. Research is focusing on photosynthesis in wheat spikes to boost yield potential. Spike photosynthesis adds on average 30% to grain yield of elite wheat lines developed at CIMMYT, but these gains can go as high as 60% in wheat’s wild relatives and landraces. The strategy is to tap into this underutilized potential to boost yields of modern wheat varieties that are also better adapted to a warming and drier world, and resistant to known and new pests and diseases. We wish to accelerate this research and are seeking a US$100 million investment in the platform.

Boosting Nitrogen Use Efficiency in Wheat

Wheat is the world’s largest nitrogen fertilizer consumer, which contributes significantly to greenhouse gas emissions and soil degradation. Groundbreaking research led by CIMMYT is increasing wheat’s ability to use nitrogen more efficiently, thereby reducing its dependency on nitrogen fertilizer by between 15% to 20%, depending on regional farming systems. Increased nitrogen use efficiency has been achieved after successfully transferring a natural ability to inhibit biological nitrification from wheat’s wild relatives to modern wheat varieties. Biological nitrification inhibition (BNI) is a natural process that provides wheat plants with a more sustained source of nitrogen available in the soil, thereby increasing their nitrogen use efficiency. BNI wheat is a game-changing innovation that will contribute to significantly reducing agriculture’s nitrogen footprint sustainably without compromising yields or grain quality. While the BNI research platform has received its first investment for wheat, an additional investment of US$30 million per crop would expand the platform to maize, millet, and sorghum.

Improving and Scaling Up ‘Opportunity Crops’

CIMMYT recently partnered with the United Nations Food and Agriculture Organization (FAO) to advance the global Vision for Adapted Crops and Soils (VACS) endorsed by the G7, which aims to sustainably increase the production of diverse, nutritious, and climate-adapted indigenous and traditional food crops grown on healthy soils. We have identified seven “opportunity crops,” including pearl millet, finger millet, pigeon pea, cowpea, mung bean, and amaranth, that can be grown sustainably and significantly improve nutrition and food security in sub-Saharan Africa. At present, the VACS partner network is working hard to develop new varieties of these opportunity crops and to build pathways for African farmers to access improved seeds and markets for their produce. The soil component of the VACS movement is underfunded, so we are looking for a US$500 million investment to launch a strong VACS Soils initiative.

A Parting Shot

Improved photosynthesis and increased nitrogen use efficiency in wheat, and nutrient-dense indigenous crops are exciting “moonshot” efforts already building resilient food systems that may help humanity avert a global food catastrophe in two decades’ time. But political will and available funding for agricultural research and development will ultimately determine if these and many more urgently needed scientific breakthroughs will reach their full potential in the fight against hunger in a more food insecure and unstable world.

Bram Govaerts is CIMMYT’s director general. He is an international authority in maize, wheat and associated cropping systems who works for a successful transformation of small-scale farming in Africa, Asia and Latin America. Govaerts advises public, private and social organizations worldwide and is an active member of research groups and associations, including the American Society of Agronomy and Cornell University’s Andrew D. White Professors-at-Large Program.

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