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funder_partner: Novo Nordisk Foundation

CropSustaiN BNI Wheat Mission

Written by Julian Bañuelos-Uribe on . Posted in Uncategorized.

The Novo Nordisk Foundation and CIMMYT have launched the 4-year CropSustaiN initiative to determine the global potential of wheat that is significantly better at using nitrogen, thanks to Biological Nitrification Inhibition (BNI)—and to accelerate breeding and farmer access to BNI wheat varieties.

With a budget of US$ 21 million, CropSustaiN addresses the pressing challenges of nitrogen pollution and inefficient fertilizer use, which contribute to greenhouse gas (GHG) emissions and ecological degradation. Currently, no other seed or agronomic practice-based solution matches BNI crops’ mitigation impact potential. Growing BNI crops can complement other climate mitigation measures.

The challenge

Agriculture is at the heart of both food and nutrition security and environmental sustainability. The sector contributes ca. 10-12% of global GHG emissions, including 80% of the highly potent nitrous oxide (N2O) emissions. Fertilizer use contributes to such N losses, because plants take up about 50%, the remainder being lost. Wheat is the world’s largest ‘crop’ consumer of nitrogen-based fertilizer—a relatively nitrogen-inefficient cereal—at the same time providing affordable calories to billions of resource-poor people and ca. 20% of globally consumed protein. CropSustaiN targets this nexus of productivity and planetary boundary impact by verifying and thus de-risking the needed breeding, agronomic, and social innovations.

A solution: BNI-wheat

BNI is a natural ability of certain plant species to release metabolites from their roots into the soil. They influence the nitrogen-transforming activity of nitrifying bacteria, slowing down the conversion of ammonium to nitrate in the soil. This preserves soil ammonium levels for a longer time, providing plants with a more sustained source of available nitrogen and making them more nitrogen-use efficient (nitrogen plant use efficiency). As a result, BNI helps reduce the release of N2O gas emissions and nitrate leaching to the surrounding ecosystem.

A research breakthrough in 2021, led by the Japan International Research Center of Agricultural Sciences (JIRCAS) in collaboration with CIMMYT, demonstrated that the BNI trait can be transferred from a wheat wild relative to a modern wheat variety by conventional breeding. BNI wheat can be made available to farmers worldwide.

Growing BNI wheat could reduce nitrogen fertilizer usage by 15-20%, depending on regional farming conditions, without sacrificing yield or quality.

 

Incorporating BNI into additional crops would reduce usage further. Farmers can get the same yield with less external inputs.

Other BNI-crops

CropSustaiN will work on spring and winter wheats. Rice, maize, barley, and sorghum also have BNI potential. CropSustaiN will build the knowledge base and share with scientists working on other crops and agronomic approaches.

Objectives and outcomes

This high risk, high reward mission aims to:

  • Verify the global, on-farm potential of BNI-wheat through field trial research and breeding.
  • Build the partnerships and pathways to meet farmer demand for BNI-wheat seeds.
  • Work with stakeholders on policy change that enables BNI crops production and markets

Success will be measured by determining nitrogen pollution reduction levels under different soil nitrogen environments and management conditions on research stations, documenting crop performance and safety, breeding for BNI spring and winter wheats for a wide range of geographies, and gauging farmer needs, interest, and future demand.

Wheat spikes against the sky at CIMMYT’s El BatĂĄn, Mexico headquarters. (Photo: H. Hernandez Lira/CIMMYT)

A collaborative effort

CIMMYT is the lead implementer of Novo Nordisk Foundation’s mission funding. CropSustaiN’s interdisciplinary, intersectoral, systems approach relies on building partnerships and knowledge-sharing within and outside this research initiative. 45+ partners are engaged in CropSustaiN.

The potential GHG emissions reduction from deploying BNI-wheat is estimated to be 0.016-0.19 gigatonnes of CO2-equivalent emissions per year, reducing 0.4-6% of total global N2O emissions annually, plus a lowering of nitrate pollution.

Impact on climate change mitigation and Nationally Determined Contributions (NDCs)

The assumption is that BNI wheat is grown in all major wheat-growing areas and that farmers will practice a behavioral shift towards lower fertilizer use and higher fertilizer use efficiency. That could lead to ca. a reduction of 17 megatons per year globally. This can help nations achieve their NDCs under the Paris Agreement.

International public goods, governance, and management

CIMMYT and the Foundation are committed to open access and the dissemination of seeds, research data, and results as international public goods. The governance and management model reinforces a commitment to equitable global access to CropSustaiN outputs, emphasized in partnership agreements and management of intellectual property.

Invitation to join the mission

The CropSustaiN initiative is a bold step towards agricultural transformation. You are invited to become a partner. You can contribute to the mission with advice, by sharing methods, research data and results, or becoming a co-founder.

Please contact CropSustaiN Mission Director, Victor Kommerell, at v.kommerell@cgiar.org or Novo Nordisk Foundation’s Senior Scientific Manager, Jeremy A. Daniel, at jad@novo.dk.

Additional reference material

  1. BNI International Consortium (Japan International Research Center for Agricultural Sciences, JIRCAS)
  2. Nitrification inhibitors: biological and synthetic (German Environment Agency, Umweltbundesamt)
  3. CropSustaiN: new innovative crops to reduce the nitrogen footprint form agriculture
  4. Annual Technical Report 2024. CropSustaiN: A new paradigm to reduce the nitrogen footprint from agriculture
  5. BNI-Wheat Future: towards reducing global nitrogen use in wheat
  6. CIMMYT Publications Repository

New innovative crops could significantly reduce agriculture’s climate change impact and environmental footprint

Written by Julian Bañuelos-Uribe on . Posted in Press releases.

As the global population approaches the 10 billion mark, the reliance on fertilisers to boost agricultural production has become an essential, yet environmentally challenging, practice. A Century-long dependence on these additives has allowed food production to keep pace with the growth in human population. However, the use of fertilisers across various farming systems is now causing severe ecological stress. The leaching of nitrogen into natural ecosystems, coupled with the release of greenhouse gases, is pushing the Earth’s environmental limits to a critical threshold.

To address this, an ambitious new research initiative aims to shrink the nitrogen footprint of agriculture by developing a breakthrough technology based on nature’s own solutions: a natural process called biological nitrification inhibition (BNI). The Novo Nordisk Foundation has awarded CIMMYT a grant of up to USD 21.1 million to lead an innovation research initiative called CropSustaiN that is designed to reduce the nitrogen footprint of wheat cultivation.

“Success in this initiative could lead to a major shift in agricultural practices globally, benefiting both the planet and farmers’ livelihoods. In addition to using less fertiliser, cost for the farmer will be minimal because all the components are already in the seed. This initiative could, potentially, be extended from wheat cultivation to include other staple crops like maize and rice,” says Claus Felby, Senior Vice President, Biotech, Novo Nordisk Foundation.

“BNI could be a part of how we revolutionise nitrogen management in agriculture. It represents a genetic mitigation strategy that not only complement existing methods but also has the potential to decrease the need for synthetic fertilisers substantially. The mitigation potential of better nitrogen fertiliser management could be as impactful for the Global South as the Green Revolution,” explains Bram Govaerts, Director General, CIMMYT.

Revolutionary mitigation approach

Rooted in a seed-based genetic strategy, BNI leverages a plant’s innate ability to suppress soil nitrification through the release of natural compounds. This approach potentially promises to curb the use and leaching of synthetic nitrogen fertilisers—a significant contributor to greenhouse gas emissions and water pollution—without compromising wheat yield or soil vitality. The BNI-method contrasts with synthetic nitrification inhibitors and could offer a more scalable and cost-effective solution, potentially reducing nitrogen fertiliser usage by 20%, depending on regional farming conditions.

By harnessing the power of genetics in plant seeds, CropSustaiN leverages the natural process of BNI to develop new wheat varieties that require significantly less nitrogen fertiliser. Using conventional breeding, genes from wild crop relatives like wild rye, which have inherently better nitrogen use efficiency, are incorporated. CIMMYT makes such breeding products available to its global network of partners for the international public good.

The agenda for CropSustaiN includes validating BNI efficacy across diverse climates and integrating the technology into mainstream agricultural protocols. While the venture carries success risks, the potential rewards—ranging from widespread BNI adoption to valuable insights into nitrogen management—position it as a pioneering initiative. By ensuring that the seeds developed through this program are accessible to all farmers without exclusive patent rights, the Novo Nordisk Foundation is leading an inclusive approach to agricultural innovation.

CropSustaiN builds on the joint research by the Japan International Research Center for Agricultural Sciences (JIRCAS) and CIMMYT that started in 2015. The initiative has already yielded BNI wheat lines tested over three farming seasons. These innovative crops are now poised for further development and for scaling worldwide, indicating a potential paradigm shift in agricultural practices.

The Novo Nordisk Foundation has already laid the groundwork for CropSustaiN by funding related BNI research at CIMMYT, the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Aarhus University, the University of Aberdeen, and the University of Copenhagen -thus fostering an ecosystem for research innovation.

About the Novo Nordisk Foundation

Established in Denmark in 1924, the Novo Nordisk Foundation is an enterprise foundation with philanthropic objectives. The vision of the Foundation is to improve people’s health and the sustainability of society and the planet. The Foundation’s mission is to progress research and innovation in the prevention and treatment of cardiometabolic and infectious diseases as well as to advance knowledge and solutions to support a green transformation of society.

www.novonordiskfonden.dk/en

About CIMMYT

CIMMYT is a cutting edge, non-profit, international organization dedicated to solving tomorrow’s problems today. It is entrusted with fostering improved quantity, quality, and dependability of production systems and basic cereals such as maize, wheat, triticale, sorghum, millets, and associated crops through applied agricultural science, particularly in the Global South, through building strong partnerships. This combination enhances the livelihood trajectories and resilience of millions of resource-poor farmers, while working towards a more productive, inclusive, and resilient agrifood system within planetary boundaries. CIMMYT is a core CGIAR Research Center, a global research partnership for a food-secure future, dedicated to reducing poverty, enhancing food and nutrition security, and improving natural resources. For more information, visit staging.cimmyt.org.

Further information 

Jakob Stein, Communications Specialist, jse@novo.dk